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dc.contributor.author | Matsuo, Yukinori | en |
dc.contributor.author | Ueki, Nami | en |
dc.contributor.author | Takayama, Kenji | en |
dc.contributor.author | Nakamura, Mitsuhiro | en |
dc.contributor.author | Miyabe, Yuki | en |
dc.contributor.author | Ishihara, Yoshitomo | en |
dc.contributor.author | Mukumoto, Nobutaka | en |
dc.contributor.author | Yano, Shinsuke | en |
dc.contributor.author | Tanabe, Hiroaki | en |
dc.contributor.author | Kaneko, Shuji | en |
dc.contributor.author | Mizowaki, Takashi | en |
dc.contributor.author | Monzen, Hajime | en |
dc.contributor.author | Sawada, Akira | en |
dc.contributor.author | Kokubo, Masaki | en |
dc.contributor.author | Hiraoka, Masahiro | en |
dc.contributor.alternative | 松尾, 幸憲 | ja |
dc.date.accessioned | 2014-12-26T04:20:08Z | - |
dc.date.available | 2014-12-26T04:20:08Z | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 0167-8140 | - |
dc.identifier.uri | http://hdl.handle.net/2433/192774 | - |
dc.description.abstract | [Purpose]To evaluate feasibility and acute toxicities after dynamic tumour tracking (DTT) irradiation with real-time monitoring for lung tumours using a gimbal mounted linac. [Materials and methods]Spherical gold markers were placed around the tumour using a bronchoscope prior to treatment planning. Prescription dose at the isocentre was 56 Gy in 4 fractions for T2a lung cancer and metastatic tumour, and 48 Gy in 4 fractions for the others. Dose-volume metrics were compared between DTT and conventional static irradiation using in-house developed software. [Results]Of twenty-two patients enrolled, DTT radiotherapy was successfully performed for 16 patients, except 4 patients who coughed out the gold markers, one who showed spontaneous tumour regression, and one where the abdominal wall motion did not correlate with the tumour motion. Dose covering 95% volume of GTV was not different between the two techniques, while normal lung volume receiving 20 Gy or more was reduced by 20%. A mean treatment time per fraction was 36 min using DTT. With a median follow-up period of 13.2 months, no severe toxicity grade 3 or worse was observed. [Conclusions]DTT radiotherapy using a gimbal mounted linac was clinically feasible for lung treatment without any severe acute toxicity. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier Ireland Ltd. | en |
dc.rights | © 2014 Elsevier Ireland Ltd. | en |
dc.rights | This is not the published version. Please cite only the published version. | en |
dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
dc.subject | Stereotactic body radiotherapy | en |
dc.subject | Lung cancer | en |
dc.subject | Dynamic tumour tracking | en |
dc.subject | Real-time monitoring | en |
dc.subject | Feasibility study | en |
dc.title | Evaluation of dynamic tumour tracking radiotherapy with real-time monitoring for lung tumours using a gimbal mounted linac. | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.ncid | AA10476884 | - |
dc.identifier.jtitle | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | en |
dc.identifier.volume | 112 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 360 | - |
dc.identifier.epage | 364 | - |
dc.relation.doi | 10.1016/j.radonc.2014.08.003 | - |
dc.textversion | author | - |
dc.identifier.pmid | 25154320 | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
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