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タイトル: | Tandem duplications in the C-terminal domain of the mesotocin receptor exclusively identified among East Eurasian thrushes. |
著者: | Abe, Hideaki Nishiumi, Isao Inoue-Murayama, Miho |
著者名の別形: | 阿部, 秀明 村山, 美穂 |
キーワード: | Mesotocin receptor C-terminal domain Tandem duplication Polymorphism Insertions and deletions Turdus |
発行日: | 6-Nov-2013 |
出版者: | Springer US |
誌名: | Journal of molecular evolution |
巻: | 77 |
号: | 5-6 |
開始ページ: | 260 |
終了ページ: | 267 |
抄録: | Mesotocin is a neurohypophyseal hormone found in some non-mammalian vertebrates, including birds, reptiles, and amphibians. In this study, we identified and characterized 18-amino acid duplications in the C-terminal domain of the mesotocin receptor (MTR), specifically found in Turdus thrushes (Aves: Passeriforms: Turdidae). These duplicated elements are located in the distal part of the C-terminal tails of MTR and consist of amino acids that are highly conserved among major vertebrates. Intraspecific polymorphisms in a variable number of tandem duplications are commonly found in East Eurasian Turdus, but not in any other genus of Turdidae. Moreover, the genus Turdus can be further classified into 2 groups according to the presence or absence of a 3-amino acid deletion just adjacent to the putative palmitoylation site in the cytoplasmic C-terminal tail. The phylogeny presented here strongly supports the conspecific group of 4 East Eurasian thrushes (Turdus pallidus, T. chrysolaus, T. obscurus, and T. celaenops). Our findings, therefore, provide a new synapomorphy that can be used for phylogenetic assumptions and shed a light on the history of diversification within Eurasian Turdus clades. |
著作権等: | The final publication is available at Springer via http://dx.doi.org/10.1007/s00239-013-9590-z この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/197381 |
DOI(出版社版): | 10.1007/s00239-013-9590-z |
PubMed ID: | 24193891 |
出現コレクション: | 学術雑誌掲載論文等 |
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