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タイトル: | インターフェロンを中心とした集学的療法で長期コントロールが可能であったGrowing teratoma syndromeの1例 |
その他のタイトル: | A Case of Growing Teratoma Syndrome; Long-Term Control Accomplished by Systemic Interferon Therapy with Adequate Local Therapies |
著者: | 吉川, 武志 植垣, 正幸 小林, 恭 根来, 宏光 山崎, 俊成 清川, 岳彦 賀本, 敏行 神波, 大己 小川, 修 |
著者名の別形: | Yoshikawa, Takeshi Uegaki, Masayuki Kobayashi, Takashi Negoro, Hiromitsu Yamasaki, Toshinari Segawa, Takehiko Kamoto, Toshiyuki Kamba, Tomomi Ogawa, Osamu |
キーワード: | Growing teratoma syndrome Interferon Multidisciplinary approach Growing teratoma syndrome Interferon Multidisciplinary approach |
発行日: | Apr-2015 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 61 |
号: | 4 |
開始ページ: | 163 |
終了ページ: | 166 |
抄録: | A 31-year-old man came to our hospital with chest pain and was diagnosed to have a left testicular tumor with metastasis to the lung, and cervical, mediastinal, and retroperitoneal lymph nodes. Left orchiectomy was performed, and histological diagnosis was seminoma. Serum tumor markers were normalized after 3rd-line chemotherapy, but lymph node metastases were still enlarged. Then the cervical lymph node was excised, and histologically diagnosed as mature teratoma. Based on these results, we diagnosed this case as growing teratoma syndrome. Since the whole metastasis was too large to be completely excised, we started systemic interferon alfa-2b (Intron ○R A) administration. The metastasis initially responded to the therapy by 20% reduction in size and remained stable thereafter. However, the mediastinal lesion caused obstructive pneumonia, which was bronchoscopically resected. At the time of 12 years after the initial presentation, the tumors are well controlled with stable disease or only modest increase. |
著作権等: | 許諾条件により本文は2016/05/01に公開 |
URI: | http://hdl.handle.net/2433/198258 |
PubMed ID: | 26037676 |
出現コレクション: | Vol. 61 No. 4 |
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