ダウンロード数: 408
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
s11418-012-0680-9.pdf | 354.41 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | Tankam, Joan Manjuh | en |
dc.contributor.author | Sawada, Yuki | en |
dc.contributor.author | Ito, Michiho | en |
dc.contributor.alternative | 伊藤, 美千穂 | ja |
dc.date.accessioned | 2015-06-17T02:52:06Z | - |
dc.date.available | 2015-06-17T02:52:06Z | - |
dc.date.issued | 2012-07-04 | - |
dc.identifier.issn | 1340-3443 | - |
dc.identifier.uri | http://hdl.handle.net/2433/198451 | - |
dc.description.abstract | The present study investigated the gastroprotective effects of a cinnamon diet using different gastric ulcer mouse models. Dose dependency and the effective dose period of administration of a cinnamon powder diet were established using the water immersion stress gastric ulcer model. A cinnamon powder diet significantly protected mice against ulceration by stress, ethanol, HCl and oral administration of aspirin, but not against ulceration by oral administration of indomethacin or subcutaneous administration of indomethacin or aspirin. Such a diet conferred protection against gastric ulcers at an effective concentration of 100 mg cinnamon powder per gram of food after administration for 4 weeks and the active compound of cinnamon powder for gastroprotective activity was identified as cinnamaldehyde. These findings indicate that regular ingestion of cinnamon powder offers gastroprotection presumably through a cytoprotective mechanism but the efficacy against NSAIDs-induced gastric ulcers may be limited. | en |
dc.language.iso | eng | - |
dc.publisher | Springer | en |
dc.rights | The final publication is available at Springer via http://dx.doi.org/10.1007/s11418-012-0680-9. | en |
dc.rights | This is not the published version. Please cite only the published version. | en |
dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
dc.subject | Cinnamomum cassia powder | en |
dc.subject | Gastric ulcer | en |
dc.subject | Gastroprotection | en |
dc.subject | Regular ingestion | en |
dc.subject | Synergism | en |
dc.subject.mesh | Acrolein/analogs & derivatives | en |
dc.subject.mesh | Acrolein/chemistry | en |
dc.subject.mesh | Acrolein/therapeutic use | en |
dc.subject.mesh | Animals | en |
dc.subject.mesh | Anti-Ulcer Agents/chemistry | en |
dc.subject.mesh | Anti-Ulcer Agents/therapeutic use | en |
dc.subject.mesh | Aspirin/adverse effects | en |
dc.subject.mesh | Cinnamomum zeylanicum/chemistry | en |
dc.subject.mesh | Disease Models, Animal | en |
dc.subject.mesh | Drugs, Chinese Herbal/chemistry | en |
dc.subject.mesh | Drugs, Chinese Herbal/therapeutic use | en |
dc.subject.mesh | Ethanol/adverse effects | en |
dc.subject.mesh | Indomethacin/adverse effects | en |
dc.subject.mesh | Male | en |
dc.subject.mesh | Mice | en |
dc.subject.mesh | Stomach Ulcer/chemically induced | en |
dc.subject.mesh | Stomach Ulcer/drug therapy | en |
dc.title | Regular ingestion of cinnamomi cortex pulveratus offers gastroprotective activity in mice. | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.ncid | AA12114658 | - |
dc.identifier.jtitle | Journal of Natural Medicines | en |
dc.identifier.volume | 67 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 289 | - |
dc.identifier.epage | 295 | - |
dc.relation.doi | 10.1007/s11418-012-0680-9 | - |
dc.textversion | author | - |
dc.startdate.bitstreamsavailable | 2013-07-04 | - |
dc.identifier.pmid | 22760889 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 1340-3443 | - |
dc.identifier.eissn | 1861-0293 | - |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。