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タイトル: | Regulatory expression of components in the BMP pathway in white adipose tissues of cattle |
著者: | Qiao, Yuhang Yamada, Tomoya Kanamori, Yohei Kida, Ryosuke Shigematsu, Mei Fujimoto, Yusuke Tomonaga, Shozo https://orcid.org/0000-0003-0888-1407 (unconfirmed) Matsui, Tohru Funaba, Masayuki https://orcid.org/0000-0002-4303-6682 (unconfirmed) |
著者名の別形: | 舟場, 正幸 |
キーワード: | BMP Brown adipocyte Beige adipocyte Cattle |
発行日: | Apr-2015 |
出版者: | Elsevier B.V. |
誌名: | Livestock Science |
巻: | 174 |
開始ページ: | 144 |
終了ページ: | 149 |
抄録: | The BMP pathway positively regulates murine brown adipogenesis. We herein examined the mRNA levels of BMPs and activin βB as well as receptors for the BMP pathway in the adipose tissues of cattle fed diets with a differential ratio of concentrate to roughage or a vitamin A-deficient diet. The expression of activin βB was significantly increased in the subcutaneous fat depot of animals fed the concentrate diet, while the vitamin A-deficient diet significantly increased the expression of BMP4 in the mesenteric fat depot. The expression of receptors for the BMP pathway, ALK2, ALK3, ActRIIA, and BMPR2, showed a similar pattern to that of BMP4 and activin βB in response to the dietary treatments. The results of the present study demonstrated that diet modulated the expression of components of the BMP pathway and may be responsible for the regulatory expression of brown/beige adipocyte-related genes in the adipose tissues of cattle. |
著作権等: | © 2015 Elsevier B.V. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/. NOTICE: this is the author's version of a work that was accepted for publication in [Livestock Science]. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in [Livestock Science, Volume 174, Pages 144–149], doi:10.1016/j.livsci.2015.02.008. 許諾条件により本文ファイルは2015-02-20に公開. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/198736 |
DOI(出版社版): | 10.1016/j.livsci.2015.02.008 |
出現コレクション: | 学術雑誌掲載論文等 |
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