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dc.contributor.authorKagohashi, Hirokien
dc.contributor.authorShirai, Osamuen
dc.contributor.authorKubota, Shintaroen
dc.contributor.authorKitazumi, Yukien
dc.contributor.authorKano, Kenjien
dc.contributor.alternative籠橋, 宏樹ja
dc.contributor.alternative白井, 理ja
dc.contributor.alternative窪田, 慎太郎ja
dc.contributor.alternative北隅, 優希ja
dc.contributor.alternative加納, 健司ja
dc.date.accessioned2015-08-20T02:35:10Z-
dc.date.available2015-08-20T02:35:10Z-
dc.date.issued2014-03-
dc.identifier.issn1040-0397-
dc.identifier.urihttp://hdl.handle.net/2433/199597-
dc.description.abstractThe transport of ions and glucose across bilayer lipid membranes (BLM) facilitated by amphotericin B (AmB) is studied by use of planar BLMs and liposomal membranes. The transport characteristics change with time in the presence of cholesterol, while it is independent of time in the absence of cholesterol. The carrier-type transport is observed immediately after the addition of AmB. In the presence of cholesterol, AmB forms a 1 : 1 complex with cholesterol and the channel is formed by aggregation of AmB-cholesterol complexes. It is concluded that the number of the channels increases with time and that the carrier-type transport decreases instead.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherWileyen
dc.rightsThis is the peer reviewed version of the following article: Kagohashi, H., Shirai, O., Kubota, S., Kitazumi, Y. and Kano, K. (2014), Facilitated Transport of Ions and Glucose by Amphotericin B Across Lipid Bilayers in the Presence or Absence of Cholesterol. Electroanalysis, 26: 625–631, which has been published in final form at http://dx.doi.org/10.1002/elan.201300555. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.en
dc.rightsThis is not the published version. Please cite only the published version.en
dc.rightsこの論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。ja
dc.subjectAmphotericin Ben
dc.subjectBilayer lipid membraneen
dc.subjectIon transporten
dc.subjectLiposomeen
dc.subjectGlucoseen
dc.subjectCholesterolen
dc.titleFacilitated Transport of Ions and Glucose by Amphotericin B Across Lipid Bilayers in the Presence or Absence of Cholesterolen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.ncidAA10739462-
dc.identifier.jtitleElectroanalysisen
dc.identifier.volume26-
dc.identifier.issue3-
dc.identifier.spage625-
dc.identifier.epage631-
dc.relation.doi10.1002/elan.201300555-
dc.textversionauthor-
dc.startdate.bitstreamsavailable2015-02-13-
dcterms.accessRightsopen access-
dc.identifier.pissn1040-0397-
dc.identifier.eissn1521-4109-
出現コレクション:学術雑誌掲載論文等

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