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タイトル: | Long-term maintenance of human induced pluripotent stem cells by automated cell culture system. |
著者: | Konagaya, Shuhei Ando, Takeshi Yamauchi, Toshiaki Suemori, Hirofumi https://orcid.org/0000-0002-3565-3111 (unconfirmed) Iwata, Hiroo |
著者名の別形: | 小長谷, 周平 岩田, 博夫 |
発行日: | 17-Nov-2015 |
出版者: | Nature Publishing Group |
誌名: | Scientific reports |
巻: | 5 |
論文番号: | 16647 |
抄録: | Pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem (iPS) cells, are regarded as new sources for cell replacement therapy. These cells can unlimitedly expand under undifferentiated conditions and be differentiated into multiple cell types. Automated culture systems enable the large-scale production of cells. In addition to reducing the time and effort of researchers, an automated culture system improves the reproducibility of cell cultures. In the present study, we newly designed a fully automated cell culture system for human iPS maintenance. Using an automated culture system, hiPS cells maintained their undifferentiated state for 60 days. Automatically prepared hiPS cells had a potency of differentiation into three germ layer cells including dopaminergic neurons and pancreatic cells. |
記述: | 自動培養装置によるヒトiPS細胞の長期間培養に成功 . 京都大学プレスリリース. 2015-11-27. |
著作権等: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
URI: | http://hdl.handle.net/2433/202017 |
DOI(出版社版): | 10.1038/srep16647 |
PubMed ID: | 26573336 |
関連リンク: | http://www.kyoto-u.ac.jp/ja/research/research_results/2015/151117_1.html |
出現コレクション: | 学術雑誌掲載論文等 |
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