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Title: Different Mode of Afferents Determines the Frequency Range of High Frequency Activities in the Human Brain: Direct Electrocorticographic Comparison between Peripheral Nerve and Direct Cortical Stimulation.
Authors: Kobayashi, Katsuya  kyouindb  KAKEN_id
Matsumoto, Riki  kyouindb  KAKEN_id  orcid (unconfirmed)
Matsuhashi, Masao  kyouindb  KAKEN_id  orcid (unconfirmed)
Usami, Kiyohide  kyouindb  KAKEN_id  orcid (unconfirmed)
Shimotake, Akihiro  kyouindb  KAKEN_id
Kunieda, Takeharu
Kikuchi, Takayuki  kyouindb  KAKEN_id
Mikuni, Nobuhiro
Miyamoto, Susumu
Fukuyama, Hidenao
Takahashi, Ryosuke  kyouindb  KAKEN_id
Ikeda, Akio  kyouindb  KAKEN_id  orcid (unconfirmed)
Author's alias: 小林, 勝哉
松本, 理器
Issue Date: 18-Jun-2015
Publisher: Public Library of Science
Journal title: PloS one
Volume: 10
Issue: 6
Thesis number: e0130461
Abstract: Physiological high frequency activities (HFA) are related to various brain functions. Factors, however, regulating its frequency have not been well elucidated in humans. To validate the hypothesis that different propagation modes (thalamo-cortical vs. cortico-coritcal projections), or different terminal layers (layer IV vs. layer II/III) affect its frequency, we, in the primary somatosensory cortex (SI), compared HFAs induced by median nerve stimulation with those induced by electrical stimulation of the cortex connecting to SI. We employed 6 patients who underwent chronic subdural electrode implantation for presurgical evaluation. We evaluated the HFA power values in reference to the baseline overriding N20 (earliest cortical response) and N80 (late response) of somatosensory evoked potentials (HFA(SEP(N20)) and HFA(SEP(N80))) and compared those overriding N1 and N2 (first and second responses) of cortico-cortical evoked potentials (HFA(CCEP(N1)) and HFA(CCEP(N2))). HFA(SEP(N20)) showed the power peak in the frequency above 200 Hz, while HFA(CCEP(N1)) had its power peak in the frequency below 200 Hz. Different propagation modes and/or different terminal layers seemed to determine HFA frequency. Since HFA(CCEP(N1)) and HFA induced during various brain functions share a similar broadband profile of the power spectrum, cortico-coritcal horizontal propagation seems to represent common mode of neural transmission for processing these functions.
Rights: © 2015 Kobayashi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DOI(Published Version): 10.1371/journal.pone.0130461
PubMed ID: 26087042
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