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タイトル: | 京都大学における前立腺導管癌の臨床的検討 |
その他のタイトル: | Clinical Characteristics of Prostate Ductal Adenocarcinoma in Kyoto University Hospital |
著者: | 中村, 健治 寺田, 直樹 小林, 恭 杉野, 善雄 山﨑, 俊成 松井, 喜之 今村, 正明 大久保, 和俊 神波, 大己 吉村, 耕治 小川, 修 |
著者名の別形: | Nakamura, Kenji Terada, Naoki Kobayashi, Takashi Sugino, Yoshio Yamasaki, Toshinari Matsui, Yoshiyuki Imamura, Masaaki Okubo, Kazutoshi Kamba, Tomomi Yoshimura, Koji Ogawa, Osamu |
キーワード: | Ductal adenocarcinoma Prostate Prostatectomy Prognosis |
発行日: | 31-Dec-2015 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 61 |
号: | 12 |
開始ページ: | 487 |
終了ページ: | 491 |
抄録: | Prostate ductal adenocarcinoma is a rare variant of prostate cancer and considered to be more aggressive than the common acinar type of adenocarcinoma. The appropriate treatment guideline for prostate ductal adenocarcinoma has not been established. The aim of the present study was to examine the clinical characteristics and the effectiveness of treatment for prostate ductal adenocarcinoma. From 2005 to 2012, 41 patients were diagnosed to have prostate ductal adenocarcinoma in Kyoto University Hospital. The mean±SD age was 68.6±7.0 years, and the median (range) initial serum PSA level was 9.3 (3.7-217) ng/ml. Among 17 patients who underwent radical prostatectomy, 10 (58.8%) had pT3 disease and 5 (29.4%) had biochemical recurrence during median follow-up of 22.9 months. Out of 19 patients treated with definitive EBRT with endocrine therapy, 2 patients (10.5%) experienced biochemical recurrence with median follow-up of 37.3 months. Five patients were treated with endocrine therapy alone, and 2 (40.0%) of them died of prostate ductal adenocarcinoma. In conclusion, patients with prostate ductal adenocarcinoma were more likely diagnosed as locally advanced diseases than those with prostate acinar adenocarcinoma. However, for patients without metastasis, either surgery or EBRT with endocrine therapy is effective with goodprognosis. |
著作権等: | 許諾条件により本文は2017/01/01に公開 |
URI: | http://hdl.handle.net/2433/203141 |
PubMed ID: | 26790762 |
出現コレクション: | Vol. 61 No. 12 |
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