<Case Report>A Case of Advanced Male Breast Cancer Successfully Treated by 5-Fluorouracil, Epirubicin and Cyclophosphamide Chemotherapy Combined with Tamoxifen

Abstract

A 79-year old male advanced breast cancer patient with metastases in lymph nodes, bones and anterior chest wall was effectively treated by a combination of chemotherapy (5-fluorouracil, epirubicin and cyclophosphamide), tamoxifen and minor surgery. Two months after five cycles of chemotherapy, all lymph node swellings disappeared. The main breast cancer and the chest wall metastatic nodule were resected under local anesthesia. He was maintained on tamoxifen alone and showed no lymph node recurrence during the follow up period of 20 months, suggesting good control of bone metastatic lesions.

多発性鎖骨上寓, 腋窩リンパ節転移, 多発性骨転移, 胸壁転移を有する79歳男性進行乳癌症例に対し, 胸壁転移巣切除生検にて Estrogen 受容体陽性を確認したのち, Tamoxifen 併用多剤化学療法 (5-Fluorouracil, Epirubicin, Cyclophosphamide) を施行した. 化学療法5回終了後約2ヶ月ですべてのリンパ節腫脹の消失をみたため, 外来にて単純乳房切断術をおこなった. 以後 Tamoxifen のみの投与にて外来で追跡し, 化学療法終了後約20ヶ月間リンパ節再発を認めず, 骨転移巣も良好に制御された現在, 患者は全く愁訴なく元気に日常生活を送っている. 小手術と組み合わせた Tamoxifen 併用多剤化学療法が著効を示した男性進行乳癌の1例を報告した.