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Title: Hemostasis management of tooth extraction in a patient with Bernard–Soulier syndrome and a severe bleeding tendency: A case report
Authors: Mishima, Sayaka  kyouindb  KAKEN_id
Nakao, Kazumasa
Ikeno, Masayuki
Bessho, Kazuhisa  kyouindb  KAKEN_id
Author's alias: 三島, 清香
中尾, 一祐
別所, 和久
Keywords: Bernard–Soulier syndrome
HLA-matched platelets
Optics method in fluorescent platelet channel
Bleeding tendency
Hemostasis management
Issue Date: Jul-2015
Publisher: Elsevier Japan KK
Journal title: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Volume: 27
Issue: 4
Start page: 525
End page: 528
Abstract: Bernard–Soulier syndrome is characterized by thrombocytopenia, giant platelets, and severe bleeding; although bleeding varies widely, it is usually evident from childhood and requires particular attention during surgeries. We extracted a fractured tooth and performed hemostasis management in a male patient with a Bernard–Soulier syndrome-related severe bleeding tendency after intracerebral hemorrhage. The preoperative platelet count was abnormally low (7 × 10[9]/L). Normal coagulability was observed. After intravenous hydrocortisone administration, he received 10 human leukocyte antigen-matched platelet units. The extraction sites were packed with gelatine sponges and a splint was used for hemostasis. Excellent hemostasis was achieved with minimal human leukocyte antigen-matched platelets.
Rights: © 2014. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
The full-text file will be made open to the public on 1 July 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。This is not the published version. Please cite only the published version.
URI: http://hdl.handle.net/2433/207519
DOI(Published Version): 10.1016/j.ajoms.2014.09.010
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