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dc.contributor.author | Sugahara, Michihiro | en |
dc.contributor.author | Song, Changyong | en |
dc.contributor.author | Suzuki, Mamoru | en |
dc.contributor.author | Masuda, Tetsuya | en |
dc.contributor.author | Inoue, Shigeyuki | en |
dc.contributor.author | Nakane, Takanori | en |
dc.contributor.author | Yumoto, Fumiaki | en |
dc.contributor.author | Nango, Eriko | en |
dc.contributor.author | Tanaka, Rie | en |
dc.contributor.author | Tono, Kensuke | en |
dc.contributor.author | Joti, Yasumasa | en |
dc.contributor.author | Kameshima, Takashi | en |
dc.contributor.author | Hatsui, Takaki | en |
dc.contributor.author | Yabashi, Makina | en |
dc.contributor.author | Nureki, Osamu | en |
dc.contributor.author | Numata, Keiji | en |
dc.contributor.author | Iwata, So | en |
dc.contributor.alternative | 菅原, 道泰 | ja |
dc.contributor.alternative | 鈴木, 守 | ja |
dc.contributor.alternative | 桝田, 哲哉 | ja |
dc.contributor.alternative | 登野, 健介 | ja |
dc.contributor.alternative | 岩田, 想 | ja |
dc.date.accessioned | 2016-04-25T04:41:45Z | - |
dc.date.available | 2016-04-25T04:41:45Z | - |
dc.date.issued | 2016-04-18 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/2433/210352 | - |
dc.description | 結晶を損傷しない新しいタンパク質結晶の輸送媒体を発見-タンパク質の結晶構造解析で新薬創生に一歩近づく. 京都大学プレスリリース. 2016-04-22. | ja |
dc.description.abstract | The grease matrix was originally introduced as a microcrystal-carrier for serial femtosecond crystallography and has been expanded to applications for various types of proteins, including membrane proteins. However, the grease-based matrix has limited application for oil-sensitive proteins. Here we introduce a grease-free, water-based hyaluronic acid matrix. Applications for proteinase K and lysozyme proteins were able to produce electron density maps at 2.3-Å resolution. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Nature Publishing Group | en |
dc.rights | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | en |
dc.title | Oil-free hyaluronic acid matrix for serial femtosecond crystallography. | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Scientific reports | en |
dc.identifier.volume | 6 | - |
dc.relation.doi | 10.1038/srep24484 | - |
dc.textversion | publisher | - |
dc.identifier.artnum | 24484 | - |
dc.identifier.pmid | 27087008 | - |
dc.relation.url | https://www.kyoto-u.ac.jp/ja/research-news/2016-04-22-0 | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
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