ダウンロード数: 178
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
v7062753.pdf | 1.02 MB | Adobe PDF | 見る/開く |
完全メタデータレコード
DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | Nakaya, Yuki | en |
dc.contributor.author | Miyazawa, Takayuki | en |
dc.contributor.alternative | 仲屋, 友喜 | ja |
dc.contributor.alternative | 宮沢, 孝幸 | ja |
dc.date.accessioned | 2016-05-16T04:45:22Z | - |
dc.date.available | 2016-05-16T04:45:22Z | - |
dc.date.issued | 2015-06-05 | - |
dc.identifier.issn | 1999-4915 | - |
dc.identifier.uri | http://hdl.handle.net/2433/210838 | - |
dc.description.abstract | Recent developments in genome sequencing techniques have led to the identification of huge numbers of endogenous retroviruses (ERV) in various mammals. ERVs, which occupy 8%–13% of mammalian genomes, are believed to affect mammalian evolution and biological diversity. Although the functional significance of most ERVs remains to be elucidated, several ERVs are thought to have pivotal roles in host physiology. We and other groups recently identified ERV envelope proteins (e.g., Fematrin-1, Syncytin-Rum1, endogenous Jaagsiekte sheep retrovirus Env) that may determine the morphogenesis of the unique fused trophoblast cells, termed trinucleate cells and syncytial plaques, found in ruminant placentas; however, there are still a number of outstanding issues with regard to the role of ERVs that remain to be resolved. Here, we review what is known about how these ERVs have contributed to the development of ruminant-specific trophoblast cells. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | en |
dc.rights | © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). | en |
dc.subject | ruminants | en |
dc.subject | endogenous retrovirus | en |
dc.subject | envelope glycoprotein | en |
dc.subject | fematrin-1 | en |
dc.subject | syncytin-rum1 | en |
dc.subject | placenta | en |
dc.subject | cell-to-cell fusion | en |
dc.title | The Roles of Syncytin-Like Proteins in Ruminant Placentation. | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Viruses | en |
dc.identifier.volume | 7 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 2928 | - |
dc.identifier.epage | 2942 | - |
dc.relation.doi | 10.3390/v7062753 | - |
dc.textversion | publisher | - |
dc.identifier.pmid | 26057168 | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。