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Title: Diffusion magnetic resonance imaging: What water tells us about biological tissues
Authors: Le Bihan, Denis
Iima, Mami  kyouindb  KAKEN_id  orcid (unconfirmed)
Author's alias: 飯間, 麻美
Issue Date: 23-Jul-2015
Publisher: Public Library of Science
Journal title: PLOS Biology
Volume: 13
Issue: 7
Thesis number: e1002203
Abstract: Since its introduction in the mid-1980s, diffusion magnetic resonance imaging (MRI), which measures the random motion of water molecules in tissues, revealing their microarchitecture, has become a pillar of modern neuroimaging. Its main clinical domain has been the diagnosis of acute brain stroke and neurogical disorders, but it is also used in the body for the detection and management of cancer lesions. It can also produce stunning maps of white matter tracks in the brain, with the potential to aid in the understanding of some psychiatric disorders. However, in order to exploit fully the potential of this method, a deeper understanding of the mechanisms that govern the diffusion of water in tissues is needed.
Rights: © 2015 Le Bihan, Iima. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
DOI(Published Version): 10.1371/journal.pbio.1002203
PubMed ID: 26204162
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