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s40064-015-1144-y.pdf | 1.07 MB | Adobe PDF | 見る/開く | |
s40064-015-1305-z.pdf | Erratum | 697.04 kB | Adobe PDF | 見る/開く |
タイトル: | The effect of Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon) and its derived ingredient methylthioacetic acid on energy metabolism during aerobic exercise |
著者: | Aoi, Wataru Takeda, Kazuya Sasaki, Azusa Hasegawa, Yuki Nakamura, Yasushi Park, Eun Young Sato, Kenji https://orcid.org/0000-0002-4891-3066 (unconfirmed) Iwasa, Masayo Nakayama, Airi Minamikawa, Mizuki Kobayashi, Yukiko Shirota, Koji Suetome, Noboru |
著者名の別形: | 佐藤, 健司 |
キーワード: | Fragrant ingredient Aerobic exercise Skeletal muscle |
発行日: | 27-Dec-2015 |
出版者: | SpringerOpen |
誌名: | SpringerPlus |
巻: | 4 |
論文番号: | 377 |
抄録: | [Purpose] We investigated the effect of Katsura-uri (Japanese pickling melon; Cucumis melo var. conomon) on energy metabolism during exercise in human and animal studies. Methods Eight healthy men (mean age, 21.4 ± 0.7 years) participated in a single-blind, crossover study. Thirty minutes after ingesting the Katsura-uri drink or placebo drink, they exercised on a cycle ergometer at 40% maximal heart rate for 30 min. Respiratory gas analysis was performed during exercise to examine oxygen consumption and substrate utilization. Blood biochemical parameters were evaluated during exercise. In the animal study, the effect of methylthioacetic acid (MTA), a Katsura-uri derived component was examined in mice. Immediately after running at 25 m/min for 30 min, biochemical parameters in the hind limb muscle and blood of mice were measured. [Results] Oxygen consumption during exercise was higher in the Katsura-uri condition (19.8 ± 3.5 mL/kg/min) than the placebo condition (18.6 ± 3.0 mL/kg/min) (P < 0.05). The elevation of blood lactate was lower in the Katsura-uri condition (1.7 ± 0.4 mM) than the placebo condition (2.2 ± 0.6 mM) 15 min after beginning exercise (P < 0.05). There was a higher positive correlation between lactate concentration and carbohydrate oxidation during exercise in the Katsura-uri condition (R2 = 0.86) compared to the placebo condition (R2 = 0.47). The decrease in intermuscular pH and the increase in blood lactate following exercise were prevented by MTA supplementation (250 ppm) with significant differences in the MTA-supplemented group compared to the control group. [Conclusions] These results suggest that the ingestion of Katsura-uri and/or MTA improves glucose metabolism and acidification in skeletal muscles during exercise in human and animal studies. |
著作権等: | © 2015, Aoi et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
URI: | http://hdl.handle.net/2433/214483 |
DOI(出版社版): | 10.1186/s40064-015-1144-y |
PubMed ID: | 26217554 |
関連リンク: | http://dx.doi.org/10.1186/s40064-015-1305-z |
出現コレクション: | 学術雑誌掲載論文等 |
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