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タイトル: | Resectable hepatoblastoma with tumor thrombus extending into the right atrium after chemotherapy: A case report |
著者: | Endo, Kosuke Yokoi, Akiko Mishima, Yasuhiko Tamaki, Akihiko Takemoto, Junkichi Morita, Keiichi Iwade, Tamaki Okata, Yuichi Fukuzawa, Hiroaki Bitoh, Yuko Hasegawa, Tomomi Yoshida, Makiko Akasaka, Yoshinobu Okajima, Hideaki Oshima, Yoshihiro Maeda, Kosaku Uemoto, Shinji |
著者名の別形: | 遠藤, 耕介 岡島, 英明 上本, 伸二 |
キーワード: | Extracorporeal circulation Chemotherapy Hepatoblastoma Tumor thrombus Resection |
発行日: | Apr-2016 |
出版者: | Elsevier Inc. |
誌名: | Journal of Pediatric Surgery Case Reports |
巻: | 7 |
開始ページ: | 20 |
終了ページ: | 22 |
抄録: | Hepatoblastoma with intraatrial tumor thrombus is relatively rare. We report a case of hepatoblastoma with tumor thrombus extending into the right atrium, which responded well to chemotherapy and was resected using extracorporeal circulation. A 4-year-old girl was referred to our hospital because of abdominal distention and tenderness. A computed tomography (CT) scan showed a large tumor occupying the left 3 segments of the liver with tumor thrombus extending into the right atrium. There was also a small intrahepatic metastasis in the right lobe of the liver. She was diagnosed with hepatoblastoma on the basis of the results of open biopsy. Neoadjuvant chemotherapy with an intense CDDP-based regimen was performed. The tumor responded well to chemotherapy, and intrahepatic metastasis became undetectable on CT scan, although the tumor thrombus remained in the right atrium. After 7 courses of chemotherapy, we performed resection using extracorporeal circulation. The postoperative course was uneventful, and adjuvant chemotherapy was started 10 days after the operation. Her serum alpha-fetoprotein (AFP) level decreased to the normal range, and she was free of disease for 1 year after the operation. Tumor resection using extracorporeal circulation can be performed safely and is justified in patients with intraatrial tumor thrombus. |
著作権等: | © 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/). |
URI: | http://hdl.handle.net/2433/215116 |
DOI(出版社版): | 10.1016/j.epsc.2016.01.004 |
出現コレクション: | 学術雑誌掲載論文等 |
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