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タイトル: | Initial characterization, dosimetric benchmark and performance validation of Dynamic Wave Arc |
著者: | Burghelea, Manuela Verellen, Dirk Poels, Kenneth Hung, Cecilia Nakamura, Mitsuhiro Dhont, Jennifer Gevaert, Thierry Van den Begin, Robbe Collen, Christine Matsuo, Yukinori https://orcid.org/0000-0002-4372-8259 (unconfirmed) Kishi, Takahiro Simon, Viorica Hiraoka, Masahiro de Ridder, Mark |
著者名の別形: | 中村, 光宏 |
キーワード: | 2D diode dosimeter Dynamic Wave Arc Noncoplanar delivery |
発行日: | 29-Apr-2016 |
出版者: | BioMed Central Ltd. |
誌名: | Radiation Oncology |
巻: | 11 |
論文番号: | 63 |
抄録: | Background: Dynamic Wave Arc (DWA) is a clinical approach designed to maximize the versatility of Vero SBRT system by synchronizing the gantry-ring noncoplanar movement with D-MLC optimization. The purpose of this study was to verify the delivery accuracy of DWA approach and to evaluate the potential dosimetric benefits. Methods: DWA is an extended form of VMAT with a continuous varying ring position. The main difference in the optimization modules of VMAT and DWA is during the angular spacing, where the DWA algorithm does not consider the gantry spacing, but only the Euclidian norm of the ring and gantry angle. A preclinical version of RayStation v4.6 (RaySearch Laboratories, Sweden) was used to create patient specific wave arc trajectories for 31 patients with various anatomical tumor regions (prostate, oligometatstatic cases, centrally-located non-small cell lung cancer (NSCLC) and locally advanced pancreatic cancer-LAPC). DWA was benchmarked against the current clinical approaches and coplanar VMAT. Each plan was evaluated with regards to dose distribution, modulation complexity (MCS), monitor units and treatment time efficiency. The delivery accuracy was evaluated using a 2D diode array that takes in consideration the multi-dimensionality of DWA during dose reconstruction. Results: In centrally-located NSCLC cases, DWA improved the low dose spillage with 20 %, while the target coverage was increased with 17 % compared to 3D CRT. The structures that significantly benefited from using DWA were proximal bronchus and esophagus, with the maximal dose being reduced by 17 % and 24 %, respectively. For prostate and LAPC, neither technique seemed clearly superior to the other; however, DWA reduced with more than 65 % of the delivery time over IMRT. A steeper dose gradient outside the target was observed for all treatment sites (p < 0.01) with DWA. Except the oligometastatic cases, where the DWA-MCSs indicate a higher modulation, both DWA and VMAT modalities provide plans of similar complexity. The average γ (3 % /3 mm) passing rate for DWA plans was 99.2 ± 1 % (range from 96.8 to 100 %). Conclusions: DWA proven to be a fully functional treatment technique, allowing additional flexibility in dose shaping, while preserving dosimetrically robust delivery and treatment times comparable with coplanar VMAT. |
著作権等: | © 2016 Burghelea et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
URI: | http://hdl.handle.net/2433/215850 |
DOI(出版社版): | 10.1186/s13014-016-0633-7 |
PubMed ID: | 27130434 |
出現コレクション: | 学術雑誌掲載論文等 |
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