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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 2016_7235757.pdf | 3.68 MB | Adobe PDF | 見る/開く |
| タイトル: | Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins |
| 著者: | Fukusumi, Hayato Shofuda, Tomoko Bamba, Yohei Yamamoto, Atsuyo Kanematsu, Daisuke Handa, Yukako Okita, Keisuke    https://orcid.org/0000-0001-5806-1090 (unconfirmed)Nakamura, Masaya Yamanaka, Shinya Okano, Hideyuki Kanemura, Yonehiro |
| 著者名の別形: | 沖田, 圭介 |
| 発行日: | 2016 |
| 出版者: | Hindawi Publishing Corporation |
| 誌名: | Stem cells international |
| 巻: | 2016 |
| 論文番号: | 7235757 |
| 抄録: | Human neural progenitor cells (hNPCs) have previously been generated from limited numbers of human induced pluripotent stem cell (hiPSC) clones. Here, 21 hiPSC clones derived from human dermal fibroblasts, cord blood cells, and peripheral blood mononuclear cells were differentiated using two neural induction methods, an embryoid body (EB) formation-based method and an EB formation method using dual SMAD inhibitors (dSMADi). Our results showed that expandable hNPCs could be generated from hiPSC clones with diverse somatic tissue origins. The established hNPCs exhibited a mid/hindbrain-type neural identity and uniform expression of neural progenitor genes. |
| 著作権等: | © 2016 Hayato Fukusumi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| URI: | http://hdl.handle.net/2433/216050 |
| DOI(出版社版): | 10.1155/2016/7235757 |
| PubMed ID: | 27212953 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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