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Title: Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase
Other Titles: 結腸直腸癌におけるKRAS遺伝子変異による代謝変化は、アスパラギン合成酵素の発現亢進を介してグルタミン欠乏に対する耐性を獲得する
Authors: Toda, Kosuke
Author's alias: 戸田, 孝祐
Keywords: Colorectal cancer
KRAS
Glutamine
Asparagine synthetase
Metabolism
Issue Date: 23-Mar-2017
Publisher: 京都大学 (Kyoto University)
Conferring University: 京都大学
Degree Level: 新制・課程博士
Degree Discipline: 博士(医学)
Degree Report no.: 甲第20239号
Degree no.: 医博第4198号
Conferral date: 2017-03-23
Degree Call no.: 新制||医||1019(附属図書館)
Degree Affiliation: 京都大学大学院医学研究科医学専攻
Examination Committee members: (主査)教授 妹尾 浩, 教授 野田 亮, 教授 武藤 学
Provisions of the Ruling of Degree: 学位規則第4条第1項該当
Rights: doi: 10.1016/j.neo.2016.09.004.
DOI: 10.14989/doctor.k20239
URI: http://hdl.handle.net/2433/225464
dc.relation.haspart: https://doi.org/10.1016/j.neo.2016.09.004.
Appears in Collections:060_1 Doctoral Dissertation (Medical Science)

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