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タイトル: | CTガイド下生検およびMTX投与歴からMTX関連リンパ増殖性疾患と診断しえた両側副腎偶発腫瘍の1例 |
その他のタイトル: | A Case of Bilateral Adrenal Incidentaloma in which MTX-Related Lymphoproliferative Disease Could Be Diagnosed by Computed Tomography-Guided Biopsy and MTX Administration History |
著者: | 北風, 宏明 松下, 慎 岡田, 紘一 湊, のり子 森, 直樹 吉岡, 俊昭 |
著者名の別形: | Kitakaze, Hiroaki Matsushita, Makoto Okada, Koichi Minato, Noriko Mori, Naoki Yoshioka, Toshiaki |
キーワード: | Adrenal glands Adrenal incidentaloma Methotrexate-associated lymphoproliferative disorder (MTX-LPD) CT guided biopsy Diffuse large B-cell lymphoma |
発行日: | 31-May-2017 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 63 |
号: | 5 |
開始ページ: | 201 |
終了ページ: | 206 |
抄録: | The patient was a 76-year-old man. Because bilateral adrenal tumor (right adrenal gland 7 cm, left adrenal gland 1.5 cm) was detected in by computed tomography (CT) in methotrexate (MTX) administration for articular rheumatism from 2011, he was referred to this hospital in February, 2016. An endocrine examination, and imaging study did not lead to a definitive diagnosis and CT-guided lower needle biopsy was performed. The pathological diagnosis was diffuse large B cell lymphoma. Also, in situ hybridization revealed EBER-positive and the diagnosis of MTX-related lymphoproliferative disease (MTXLPD) was made in conjunction with the medical history. After MTX cancellation, the tumor became markedly smaller. The annual incidence of this disorder in the RA patients during MTX internal use is reported as 0.06%. According to the site of origin, lymphatic extranodal disease accounts for approximately half of the cases, but this is the third case of primary adrenal origin reported. |
著作権等: | 許諾条件により本文は2018/06/01に公開 |
DOI: | 10.14989/ActaUrolJap_63_5_201 |
URI: | http://hdl.handle.net/2433/226073 |
PubMed ID: | 28625027 |
出現コレクション: | Vol.63 No.5 |
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