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Title: Developmental trajectory of the corpus callosum from infancy to the juvenile stage: Comparative MRI between chimpanzees and humans
Authors: Sakai, Tomoko
Mikami, Akichika
Suzuki, Juri  kyouindb  KAKEN_id
Miyabe-Nishiwaki, Takako  kyouindb  KAKEN_id
Matsui, Mie
Tomonaga, Masaki  kyouindb  KAKEN_id  orcid (unconfirmed)
Hamada, Yuzuru
Matsuzawa, Tetsuro  kyouindb  KAKEN_id
Okano, Hideyuki
Oishi, Kenichi
Author's alias: 酒井, 朋子
三上, 章允
鈴木, 樹理
宮部, 貴子
友永, 雅己
濱田, 穣
松沢, 哲郎
Issue Date: 27-Jun-2017
Publisher: Public Library of Science (PLoS)
Journal title: PLOS ONE
Volume: 12
Issue: 6
Thesis number: e0179624
Abstract: How brains develop during early life is one of the most important topics in neuroscience because it underpins the neuronal functions that mature during this period. A comparison of the neurodevelopmental patterns among humans and nonhuman primates is essential to infer evolutional changes in neuroanatomy that account for higher-order brain functions, especially those specific to humans. The corpus callosum (CC) is the major white matter bundle that connects the cerebral hemispheres, and therefore, relates to a wide variety of neuronal functions. In humans, the CC area rapidly expands during infancy, followed by relatively slow changes. In chimpanzees, based on a cross-sectional study, slow changes in the CC area during the juvenile stage and later have also been reported. However, little is known about the developmental changes during infancy. A longitudinal study is also required to validate the previous cross-sectional observations about the chimpanzee CC. The present longitudinal study of magnetic resonance imaging scans demonstrates that the CC development in chimpanzees and humans is characterized by a rapid increase during infancy, followed by gradual increase during the juvenile stage. Several differences between the two species were also identified. First, there was a tendency toward a greater increase in the CC areas during infancy in humans. Second, there was a tendency toward a greater increase in the rostrum during the juvenile stage in chimpanzees. The rostral body is known to carry fibers between the bilateral prefrontal and premotor cortices, and is involved in behavior planning and control, verbal working memory, and number conception. The rostrum is known to carry fibers between the prefrontal cortices, and is involved in attention control. The interspecies differences in the developmental trajectories of the rostral body and the rostrum might be related to evolutional changes in the brain systems.
Description: チンパンジーとヒトの脳梁の発達を比較 --ヒト特有の言語、数概念に関わる神経の成熟は乳児期が鍵--. 京都大学プレスリリース. 2017-07-14.
Rights: © 2017 Sakai et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DOI(Published Version): 10.1371/journal.pone.0179624
PubMed ID: 28654656
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