Downloads: 125
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
internalmedicine.55.5227.pdf | 135.27 kB | Adobe PDF | View/Open |
Title: | Clinical and radiographic comparison of influenza virus-associated pneumonia among three viral subtypes |
Authors: | Ishiguro, Takashi Takayanagi, Noboru Kanauchi, Tetsu Uozumi, Ryuji ![]() ![]() ![]() Kawate, Eriko Takaku, Yotaro Kagiyama, Naho Shimizu, Yoshihiko Hoshi, Toshiko Morita, Satoshi Sugita, Yutaka |
Author's alias: | 魚住, 龍史 森田, 智視 |
Keywords: | influenza pneumonia subtypes computed tomography |
Issue Date: | 2016 |
Publisher: | Japanese Society of Internal Medicine |
Journal title: | Internal Medicine |
Volume: | 55 |
Issue: | 7 |
Start page: | 731 |
End page: | 737 |
Abstract: | [Objective] Presently, the predominant subtypes of influenza viruses in the world, except for those in local epidemics, include influenza pandemic H1N1 2009 (pH1N1), H3N2, and B viruses. There are few reports on the differences in the clinical features, radiographic findings, treatment, and outcomes of influenza virus-associated pneumonia among these three viral subtypes. The purpose of this study was to investigate whether the clinical features, radiographic findings, treatment, and outcomes differ among the viral subtypes. [Methods] We retrospectively analyzed 96 patients with influenza virus-associated pneumonia whose viral subtypes were clarified. [Results] Patients with pH1N1 virus-associated pneumonia tended to be young. The frequency of primary viral pneumonia differed among the virus-associated pneumonia subtypes (pH1N1, 80%; H3N2, 26.5%; and B, 31%). Patients with pH1N1 virus-associated pneumonia more frequently showed bilateral ground-glass opacities (GGOs), which affected more lobes than in patients with H3N2 and B virus-associated pneumonia. However, patients with H3N2 virus-associated pneumonia showed a higher frequency of consolidation and diffuse bronchial wall thickening than did the patients with pH1N1 virus-associated pneumonia. The severity and mortality did not differ among the three pneumonia subtypes. [Conclusion] In the patients who developed influenza virus-associated pneumonia, those with pH1N1 virus-associated pneumonia frequently developed primary viral pneumonia resulting in bilateral and broad areas of GGOs on imaging, whereas patients with H3N2 virus-associated pneumonia frequently showed consolidation and diffuse bronchial wall thickening on pulmonary imaging. |
Rights: | © 2016 The Japanese Society of Internal Medicine The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
URI: | http://hdl.handle.net/2433/226549 |
DOI(Published Version): | 10.2169/internalmedicine.55.5227 |
PubMed ID: | 27041156 |
Appears in Collections: | Journal Articles |

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.