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dc.contributor.author | Matsumoto, Yoshiaki | en |
dc.contributor.author | Asao, Yasufumi | en |
dc.contributor.author | Sekiguchi, Hiroyuki | en |
dc.contributor.author | Yoshikawa, Aya | en |
dc.contributor.author | Ishii, Tomoko | en |
dc.contributor.author | Nagae, Ken-ichi | en |
dc.contributor.author | Kobayashi, Shuichi | en |
dc.contributor.author | Tsuge, Itaru | en |
dc.contributor.author | Saito, Susumu | en |
dc.contributor.author | Takada, Masahiro | en |
dc.contributor.author | Ishida, Yoshihiro | en |
dc.contributor.author | Kataoka, Masako | en |
dc.contributor.author | Sakurai, Takaki | en |
dc.contributor.author | Yagi, Takayuki | en |
dc.contributor.author | Kabashima, Kenji | en |
dc.contributor.author | Suzuki, Shigehiko | en |
dc.contributor.author | Togashi, Kaori | en |
dc.contributor.author | Shiina, Tsuyoshi | en |
dc.contributor.author | Toi, Masakazu | en |
dc.contributor.alternative | 松本, 純明 | ja |
dc.contributor.alternative | 浅尾, 恭史 | ja |
dc.contributor.alternative | 関口, 博之 | ja |
dc.contributor.alternative | 吉川, 彩 | ja |
dc.contributor.alternative | 石井, 智子 | ja |
dc.contributor.alternative | 長永, 兼一 | ja |
dc.contributor.alternative | 小林, 秀一 | ja |
dc.contributor.alternative | 津下, 到 | ja |
dc.contributor.alternative | 齊藤, 晋 | ja |
dc.contributor.alternative | 高田, 正泰 | ja |
dc.contributor.alternative | 石田, 雄大 | ja |
dc.contributor.alternative | 片岡, 正子 | ja |
dc.contributor.alternative | 櫻井, 孝規 | ja |
dc.contributor.alternative | 八木, 隆行 | ja |
dc.contributor.alternative | 椛島, 健治 | ja |
dc.contributor.alternative | 鈴木, 茂彦 | ja |
dc.contributor.alternative | 富樫, かおり | ja |
dc.contributor.alternative | 椎名, 毅 | ja |
dc.contributor.alternative | 戸井, 雅和 | ja |
dc.date.accessioned | 2018-10-26T00:02:36Z | - |
dc.date.available | 2018-10-26T00:02:36Z | - |
dc.date.issued | 2018-10-08 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/2433/234814 | - |
dc.description | 光超音波イメージングで人体の精細な動静脈像を得ることに成功 --腫瘍血管の解析や再建手術への応用に期待--. 京都大学プレスリリース. 2018-10-25. | ja |
dc.description.abstract | Photoacoustic (PA) imaging (PAI) has been shown to be a promising tool for non-invasive blood vessel imaging. A PAI system comprising a hemispherical detector array (HDA) has been reported previously as a method providing high morphological reproducibility. However, further improvements in diagnostic capability will require improving the image quality of PAI and fusing functional and morphological imaging. Our newly developed PAI system prototype not only enhances the PA image resolution but also acquires ultrasonic (US) B-mode images at continuous positions in the same coordinate axes. In addition, the pulse-to-pulse alternating laser irradiation shortens the measurement time difference between two wavelengths. We scanned extremities and breasts in an imaging region 140 mm in diameter and obtained 3D-PA images of fine blood vessels, including arterioles and venules. We could estimate whether a vessel was an artery or a vein by using the S-factor obtained from the PA images at two wavelengths, which corresponds approximately to the haemoglobin oxygen saturation. Furthermore, we observed tumour-related blood vessels around breast tumours with unprecedented resolution. In the future, clinical studies with our new PAI system will help to elucidate various mechanisms of vascular-associated diseases and events. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Springer Nature America, Inc | en |
dc.rights | © The Author(s) 2018. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | en |
dc.subject | Breast cancer | en |
dc.subject | Imaging | en |
dc.title | Visualising peripheral arterioles and venules through high-resolution and large-area photoacoustic imaging | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Scientific Reports | en |
dc.identifier.volume | 8 | - |
dc.relation.doi | 10.1038/s41598-018-33255-8 | - |
dc.textversion | publisher | - |
dc.identifier.artnum | 14930 | - |
dc.identifier.pmid | 30297721 | - |
dc.relation.url | https://www.kyoto-u.ac.jp/ja/research-news/2018-10-25 | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
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