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dc.contributor.authorNakamura, Hughen
dc.contributor.authorYoshida, Takumaen
dc.contributor.authorTsukano, Chihiroen
dc.contributor.authorTakemoto, Yoshijien
dc.contributor.alternative中村, 斐有ja
dc.contributor.alternative吉田, 拓馬ja
dc.contributor.alternative塚野, 千尋ja
dc.contributor.alternative竹本, 佳司ja
dc.date.accessioned2019-01-07T05:21:55Z-
dc.date.available2019-01-07T05:21:55Z-
dc.date.issued2016-05-06-
dc.identifier.issn1523-7052-
dc.identifier.urihttp://hdl.handle.net/2433/235940-
dc.description.abstractCPZEN-45 was developed as an antibiotic against Mycobacterium tuberculosis by the chemical modification of caprazamycins. CPZEN-45 has been synthesized in this study by the Cu-catalyzed intramolecular amidation of a complex vinyl iodide precursor bearing uridine and sugar moieties with a secondary amide, allowing for the construction of its 1, 4-diazepin-2-one core.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherAmerican Chemical Societyen
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.6b00943.en
dc.rightsこの論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。ja
dc.rightsThis is not the published version. Please cite only the published version.en
dc.titleSynthesis of CPZEN-45: Construction of the 1,4-Diazepin-2-one Core by the Cu-Catalyzed Intramolecular Amidation of a Vinyl Iodideen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.jtitleOrganic Lettersen
dc.identifier.volume18-
dc.identifier.issue9-
dc.identifier.spage2300-
dc.identifier.epage2303-
dc.relation.doi10.1021/acs.orglett.6b00943-
dc.textversionauthor-
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.identifier.pmid27088563-
dcterms.accessRightsopen access-
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