低侵襲性人工血管の開発 (Topology optimization theory and applications toward wide fields of natural sciences)

Abstract

In this article, we report on-going projects about developments of less-invasive artificial blood tubes (Graft) for Hemodyalysis. Blood is flowing over 2m/s because of pressure gradient between artery and vein which are connected by the Graft. It causes a stenosis at the junction between the Graft and the vein, and finally the stenosis raises low efficiency of the Hemodyalysis and more infection disease. For solving this problem, we develop the graft with a sudden contraction (FCG: Flow Control Graft), and some animal experiments provide enough evidence of effectiveness. Now, by operating shape optimization, more efficient and less invasive FCG is developed.