ダウンロード数: 128
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.bmc.2018.11.044.pdf | 5.1 MB | Adobe PDF | 見る/開く |
| タイトル: | Electron injection from mitochondrial transcription factor A to DNA associated with thymine dimer photo repair |
| 著者: | Hashiya, Fumitaka Ito, Shinji Sugiyama, Hiroshi    https://orcid.org/0000-0001-8923-5946 (unconfirmed) |
| 著者名の別形: | 橋谷, 文貴 伊藤, 慎二 杉山, 弘 |
| キーワード: | Bromouracil Electron transfer Mitochondria Photochemical TFAM |
| 発行日: | 15-Jan-2019 |
| 出版者: | Elsevier Ltd |
| 誌名: | Bioorganic and Medicinal Chemistry |
| 巻: | 27 |
| 号: | 2 |
| 開始ページ: | 278 |
| 終了ページ: | 284 |
| 抄録: | Electron transfer through π-stacked arrays of double-stranded DNA contributes to the redox chemistry of bases, including guanine oxidation and thymine–thymine dimer repair by photolyase. 5-Bromouracil is an attractive photoreactive thymine analogue that can be used to investigate electron transfer in DNA, and is a useful probe for protein–DNA interaction analysis. In the present study using BrU we found that UV irradiation facilitated electron injection from mitochondrial transcription factor A into DNA. We also observed that this electron injection could lead to repair of a thymine–thymine dimer. |
| 著作権等: | © 2018 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/BY-NC-ND/4.0/). |
| URI: | http://hdl.handle.net/2433/241651 |
| DOI(出版社版): | 10.1016/j.bmc.2018.11.044 |
| PubMed ID: | 30552005 |
| 出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。