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dc.contributor.authorHirai, Mihoen
dc.contributor.authorIto, Michihoen
dc.contributor.alternative伊藤, 美千穂ja
dc.date.accessioned2019-06-25T07:51:38Z-
dc.date.available2019-06-25T07:51:38Z-
dc.date.issued2018-01-
dc.identifier.issn1340-3443-
dc.identifier.issn1861-0293-
dc.identifier.urihttp://hdl.handle.net/2433/242232-
dc.description.abstractThe sedative effects of the essential oil released by living Ocimum basilicum (basil) plants were investigated using a mouse activity monitoring system. Ocimum basilicum plants were grown in a hydroponic chamber, and either the headspace air from the hydroponic chamber or the essential oil extracted from mature plants was administered by the inhalation route to mice in an open field test. The most effective dose of O. basilicum essential oil for reducing the locomotor activity of the mice was found to be 4.0 × 10⁻³ mg per cage. The headspace air was administered to mice held in a glass cage via a Teflon tube connected to a hydroponic chamber containing O. basilicum plants. A significant decrease in locomotor activity was observed when the hydroponic chamber contained nine plants. The results of this study demonstrate that the headspace air of living basil plants could effectively reduce the locomotor activity of mice.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherSpringer Natureen
dc.rightsThis is a post-peer-review, pre-copyedit version of an article published in Journal of Natural Medicines. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11418-018-1253-3.en
dc.rightsThe full-text file will be made open to the public on 20 October 2019 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.en
dc.rightsこの論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。ja
dc.rightsThis is not the published version. Please cite only the published version.en
dc.subjectSedativeen
dc.subjectInhalationen
dc.subjectOcimum basilicumen
dc.subjectEugenolen
dc.subject(R)-(−)-Linaloolen
dc.titleSedative effects of the essential oil and headspace air of Ocimum basilicum by inhalation in miceen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.ncidAA12114658-
dc.identifier.jtitleJournal of Natural Medicinesen
dc.identifier.volume73-
dc.identifier.issue1-
dc.identifier.spage283-
dc.identifier.epage288-
dc.relation.doi10.1007/s11418-018-1253-3-
dc.textversionauthor-
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.addressGraduate School of Pharmaceutical Sciences, Kyoto Universityen
dc.identifier.pmid30343352-
dcterms.accessRightsopen access-
datacite.date.available2019-10-20-
dc.identifier.pissn1340-3443-
dc.identifier.eissn1861-0293-
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