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このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| cpb.c17-00054.pdf | 1.09 MB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Okitsu, Takashi | en |
| dc.contributor.author | Matsuyama, Take | en |
| dc.contributor.author | Yamashita, Takahiro | en |
| dc.contributor.author | Ishizuka, Toru | en |
| dc.contributor.author | Yawo, Hiromu | en |
| dc.contributor.author | Imamoto, Yasushi | en |
| dc.contributor.author | Shichida, Yoshinori | en |
| dc.contributor.author | Wada, Akimori | en |
| dc.contributor.alternative | 山下, 高廣 | ja |
| dc.contributor.alternative | 今元, 泰 | ja |
| dc.contributor.alternative | 七田, 芳則 | ja |
| dc.date.accessioned | 2019-07-23T01:10:39Z | - |
| dc.date.available | 2019-07-23T01:10:39Z | - |
| dc.date.issued | 2017-04-01 | - |
| dc.identifier.issn | 0009-2363 | - |
| dc.identifier.issn | 1347-5223 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/243170 | - |
| dc.description.abstract | Red-shifted channelrhodopsins (ChRs) are attractive for optogenetic tools. We developed a new type of red-shifted ChRs that utilized noncovalent incorporation of retinal and 3, 4-dehydroretinal-based enamine-type Schiff bases and mutated channelopsin, C1C2-K296G. These ChRs exhibited absorption maxima that were shifted 10–30 nm toward longer wavelengths than that of C1C2-ChR regenerated with all-trans-retinal. | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | Pharmaceutical Society of Japan | en |
| dc.publisher.alternative | 日本薬学会 | ja |
| dc.rights | © 2017 The Pharmaceutical Society of Japan | en |
| dc.rights | 許諾条件に基づいて掲載しています。 | ja |
| dc.subject | channelrhodopsin | en |
| dc.subject | chromophore | en |
| dc.subject | red-shift | en |
| dc.subject | neuroscience | en |
| dc.subject | optogenetics | en |
| dc.title | Alternative Formation of Red-Shifted Channelrhodopsins: Noncovalent Incorporation with Retinal-Based Enamine-Type Schiff Bases and Mutated Channelopsin | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.ncid | AA00602100 | - |
| dc.identifier.jtitle | Chemical and Pharmaceutical Bulletin | en |
| dc.identifier.volume | 65 | - |
| dc.identifier.issue | 4 | - |
| dc.identifier.spage | 356 | - |
| dc.identifier.epage | 358 | - |
| dc.relation.doi | 10.1248/cpb.c17-00054 | - |
| dc.textversion | publisher | - |
| dc.address | Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University | en |
| dc.address | Retinal Regeneration Lab, RIKEN Center for Developmental Biology | en |
| dc.address | Department of Biophysics, Graduate School of Science, Kyoto University | en |
| dc.address | Department of Developmental Biology and Neuroscience, Graduate School of Life Sciences, Tohoku University | en |
| dc.address | Department of Developmental Biology and Neuroscience, Graduate School of Life Sciences, Tohoku University | en |
| dc.address | Department of Biophysics, Graduate School of Science, Kyoto University | en |
| dc.address | Department of Biophysics, Graduate School of Science, Kyoto University | en |
| dc.address | Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University | en |
| dc.identifier.pmid | 28381675 | - |
| dc.relation.NAID | 130005529782 | - |
| dcterms.accessRights | open access | - |
| datacite.awardNumber | 26450146 | - |
| dc.identifier.pissn | 0009-2363 | - |
| dc.identifier.eissn | 1347-5223 | - |
| jpcoar.funderName | 日本学術振興会 | ja |
| jpcoar.funderName.alternative | Japan Society for the Promotion of Science (JSPS) | en |
| 出現コレクション: | 学術雑誌掲載論文等 | |
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