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Title: IgG4関連後腹膜線維症と鑑別を要した悪性リンパ腫の1例
Other Titles: A Case of Malignant Lymphoma with an Elevated Serum IgG4
Authors: 今井, 一登  KAKEN_name
坂元, 宏匡  KAKEN_name
中嶋, 正和  KAKEN_name
赤羽, 瑞穂  KAKEN_name
井尾, 克宏  KAKEN_name
河合, 潤  KAKEN_name
青山, 輝義  KAKEN_name
Author's alias: Imai, Kazuto
Sakamoto, Hiromasa
Nakashima, Masakazu
Akahane, Mizuho
Io, Katsuhiro
Kawai, Jun
Aoyama, Teruyoshi
Keywords: Malignant lymphoma
Retroperitoneal fibrosis
IgG4-related disease
Issue Date: 31-Aug-2019
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要 = Acta urologica Japonica
Volume: 65
Issue: 8
Start page: 323
End page: 328
Abstract: A man in his 60s was referred to our hospital for further examination of left hydronephrosis and renal dysfunction. An enhanced abdominal computed tomographic scan showed that the patient had chronic abdominal aortic dissection and a non-enhancing retroperitoneal soft tissue occupying the front of the abdominal aorta as well as the bilateral common iliac arteries. The left ureter was compressed by the soft tissue at the fourth lumbar level. No tumor markers were significantly elevated and idiopathic retroperitoneal fibrosis was suspected to be the cause. Before starting treatment, however, right hydronephrosis was newly observed. We placed bilateral ureteral stents and reviewed our diagnosis. Elevated serum IgG4 and accumulation of 18F-fluorodeoxyglucose in the soft tissue were the points at issue. To determine the diagnosis, we performed open wedge biopsy. Histopathological findings showed mainly fibrous connective tissue with lymphocytic infiltration, which was positive for CD10, CD20, and bcl-2. These findings indicated follicular lymphoma. Induction chemotherapy was performed with 6 cycles of rituximab/cyclophosphamide/vincristine/prednisolone. The soft tissue tumor shrank markedly and the patient has been free from bilateral ureteral stents.
Rights: 許諾条件により本文は2020/09/01に公開
DOI: 10.14989/ActaUrolJap_65_8_323
PubMed ID: 31501400
Appears in Collections:Vol.65 No.8

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