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タイトル: | Appetite-enhancing Effects of trans -Cinnamaldehyde, Benzylacetone and 1-Phenyl-2-butanone by Inhalation |
著者: | Ogawa, Kakuyou Ito, Michiho https://orcid.org/0000-0001-9821-0628 (unconfirmed) |
著者名の別形: | 伊藤, 美千穂 |
キーワード: | trans-cinnamaldehyde benzylacetone 1-phenyl-2-butanone appetite enhancement inhalation neuropeptide Y |
発行日: | Jan-2016 |
出版者: | Georg Thieme Verlag |
誌名: | Planta Medica |
巻: | 82 |
開始ページ: | 84 |
終了ページ: | 88 |
抄録: | Fragrance in the air and odours of foods and drinks are reported to affect feeding behaviours of humans and other animals. Many previous studies focusing on the relationship between fragrance and appetite have described a reduction of food intake by fragrance administration to help prevent lifestyle diseases. Aromatic herbal medicines, such as cinnamon bark and fennel fruit, are considered to have appetite-enhancing effects and they are often blended in stomachics for relief of asitia and gastric distress in Japan. These fragrant herbal medicines contain many essential oils and their fragrances are hypothesised to be active substances. In this study, food intake and the expression of neuropeptide Y and proopiomelanocortin in the hypothalamus after inhalation of fragrant compounds or essential oils were investigated in mice. Food intake was increased 1.2-fold and the neuropeptide Y mRNA expression in the hypothalamus was increased significantly in mice that inhaled trans-cinnamaldehyde, benzylacetone or 1-phenyl-2-butanone, compared with the control group. These compounds might be effective for treating loss of appetite (anorexia) or eating disorders in elderly and infirm people via a non-invasive route of administration, namely, inhalation. |
著作権等: | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. 許諾条件に基づいて掲載しています。 |
URI: | http://hdl.handle.net/2433/244238 |
DOI(出版社版): | 10.1055/s-0035-1558087 |
PubMed ID: | 26756819 |
出現コレクション: | 学術雑誌掲載論文等 |
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