ダウンロード数: 139
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
circj.CJ-19-0247.pdf | 2.07 MB | Adobe PDF | 見る/開く |
タイトル: | Reasons for Choosing Conservative Management in Symptomatic Patients With Severe Aortic Stenosis --Observations From the CURRENT AS Registry-- |
著者: | Ishii, Mitsuru Taniguchi, Tomohiko Morimoto, Takeshi Ogawa, Hisashi Masunaga, Nobutoyo Abe, Mitsuru Yoshikawa, Yusuke Shiomi, Hiroki ![]() ![]() Ando, Kenji Kanamori, Norio Murata, Koichiro Kitai, Takeshi Kawase, Yuichi Izumi, Chisato Miyake, Makoto Mitsuoka, Hirokazu Kato, Masashi Hirano, Yutaka Matsuda, Shintaro Nagao, Kazuya Inada, Tsukasa Mabuchi, Hiroshi Takeuchi, Yasuyo Yamane, Keiichiro Toyofuku, Mamoru Minamino-Muta, Eri Kato, Takao ![]() ![]() ![]() Inoko, Moriaki Ikeda, Tomoyuki Komasa, Akihiro Ishii, Katsuhisa Hotta, Kozo Higashitani, Nobuya Kato, Yoshihiro Inuzuka, Yasutaka Jinnai, Toshikazu Morikami, Yuko Akao, Masaharu Minatoya, Kenji Kimura, Takeshi |
著者名の別形: | 谷口, 智彦 南野-牟田, 恵里 加藤, 貴雄 湊谷, 謙司 木村, 剛 |
キーワード: | Aortic stenosis Prognosis Severity Treatment strategy |
発行日: | Sep-2019 |
出版者: | Japanese Circulation Society |
誌名: | Circulation Journal |
巻: | 83 |
号: | 9 |
開始ページ: | 1944 |
終了ページ: | 1953 |
抄録: | Background:There has not been a previous report on the long-term outcomes of those patients who refuse aortic valve replacement (AVR) despite physicians’ recommendations. Methods and Results:Among 3, 815 consecutive patients with severe aortic stenosis (AS) enrolled in the CURRENT AS registry, the study population comprised 2, 005 symptomatic patients, who were subdivided into 3 groups by their treatment strategy and the reasons for conservative strategy (Initial AVR group: n=905; Patient rejection group: n=256; Physician judgment group, n=844). The primary outcome measure was a composite of aortic valve-related death and heart failure hospitalization. Patients in the patient rejection group as compared with those in the physician judgment group were younger, and had less comorbidities, and lower surgical risk scores. The cumulative 5-year incidence of the primary outcome measure in the patient rejection group was markedly higher than that in the initial AVR group, and was similar to that in the physician judgment group (60.7%, 19.0%, and 66.4%, respectively). Conclusions:Patient rejection was the reason for non-referral to AVR in nearly one-quarter of the symptomatic patients with severe AS who were managed conservatively. The dismal outcome in patients who refused AVR was similar to that in patients who were not referred to AVR based on physician judgment despite less comorbidities and lower surgical risk scores in the former than in the latter. |
著作権等: | © 2019 THE JAPANESE CIRCULATION SOCIETY Publisher permitted to deposit this paper on this repository. |
URI: | http://hdl.handle.net/2433/244317 |
DOI(出版社版): | 10.1253/circj.CJ-19-0247 |
PubMed ID: | 31316039 |
出現コレクション: | 学術雑誌掲載論文等 |
![](/dspace/image/articlelinker.gif)
このリポジトリに保管されているアイテムはすべて著作権により保護されています。