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j.stemcr.2019.08.003.pdf523.86 kBAdobe PDF見る/開く
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dc.contributor.authorSawai, Tsutomuen
dc.contributor.authorSakaguchi, Hideyaen
dc.contributor.authorThomas, Elizabethen
dc.contributor.authorTakahashi, Junen
dc.contributor.authorFujita, Misaoen
dc.contributor.alternative澤井, 努ja
dc.contributor.alternative坂口, 秀哉ja
dc.contributor.alternative髙橋, 淳ja
dc.contributor.alternative藤田, みさおja
dc.date.accessioned2019-10-28T02:05:47Z-
dc.date.available2019-10-28T02:05:47Z-
dc.date.issued2019-09-10-
dc.identifier.issn2213-6711-
dc.identifier.urihttp://hdl.handle.net/2433/244388-
dc.description.abstractRecently, the use of three-dimensional neural tissues cultured in vitro and called "cerebral organoids" has advanced recapitulation of neural development and disease modeling studies. Along with such advances, cerebral organoid research, and associated concerns call for the elucidation of two points: (1) how cerebral organoid research is currently progressing and the future directions it is likely to take, especially in functional assessment of organoids, and (2) how we should solve ethical issues of possible consciousness in cerebral organoid research. This paper aims first to explore these two issues, and then to present implications and prospects for future cerebral organoid research.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherCell Pressen
dc.rights© 2019 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).en
dc.subjectneuroethicsen
dc.subjectcerebral organoidsen
dc.subjectorganoidsen
dc.subjectpluripotent stem cellsen
dc.subjectconsciousnessen
dc.subjectmoral statusen
dc.subjectfunctional assessmenten
dc.subjectneural networken
dc.titleThe Ethics of Cerebral Organoid Research: Being Conscious of Consciousnessen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.jtitleStem Cell Reportsen
dc.identifier.volume13-
dc.identifier.spage440-
dc.identifier.epage447-
dc.relation.doi10.1016/j.stemcr.2019.08.003-
dc.textversionpublisher-
dc.addressUehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research and Application, Kyoto University･Institute for the Advanced Study of Human Biology (WPI-ASHBi), KUIAS Kyoto Universityen
dc.addressDepartment of Clinical Application, Center for iPS Cell Research and Application, Kyoto Universityen
dc.addressPembroke College, University of Oxforden
dc.addressDepartment of Clinical Application, Center for iPS Cell Research and Application, Kyoto Universityen
dc.addressUehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research and Application, Kyoto University･Institute for the Advanced Study of Human Biology (WPI-ASHBi), KUIAS Kyoto Universityen
dc.identifier.pmid31509736-
dcterms.accessRightsopen access-
datacite.awardNumber17K13843-
datacite.awardNumber17J10294-
datacite.awardNumber18K15046-
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
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