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Title: 精索原発脱分化型脂肪肉腫の1例
Other Titles: A Case of Dedifferentiated Liposarcoma of the Spermatic Cord
Authors: 飛梅, 基  KAKEN_name
青木, 重之  KAKEN_name
山田, 芳彰  KAKEN_name
原, 浩司  KAKEN_name
村松, 洋行  KAKEN_name
西川, 源也  KAKEN_name
小野, 謙三  KAKEN_name
中村, 小源太  KAKEN_name
Author's alias: Tobiume, Motoi
Aoki, Shigeyuki
Yamada, Yoshiaki
Hara, Koji
Muramatsu, Hiroyuki
Nishikawa, Genya
Ono, Kenzo
Nakamura, Kogenta
Keywords: Liposarcoma
Spermatic cord
Dedifferentiation
MDM 2
CDK 4
Issue Date: 31-Oct-2019
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要 = Acta urologica Japonica
Volume: 65
Issue: 10
Start page: 429
End page: 434
Abstract: Liposarcomas are most commonly found in the extremities, in the retroperitoneum and, less often, in the head and neck area. The spermatic cord is a rare site of origin, accounting for about 4-7% of all liposarcomas. We report a case of dedifferentiated liposarcoma of the spermatic cord. A 51-year-old man was referred to our hospital for a painless hard mass in the left inguinal region. Abdominal computed tomography showed a left spermatic cord mass measuring 70 mm in diameter. We performed left high orchiectomy with resection of the mass. Immunohistochemical analysis revealed positive for murine double minute 2 (MDM 2) and cyclin dependent kinase 4 (CDK 4). Therefore, this sarcoma was diagnosed to be dedifferentiated liposarcoma. Since the surgical margin was positive, an additional wide resection including the surrounding normal tissue was performed. Complete excision was achieved after re-resection. He was alive 12 months postoperatively without any signs of recurrence. Dedifferentiated liposarcoma of the spermatic cord is a rare neoplasm. To the best of our knowledge, the present case is the 14th reported case in Japan.
Rights: 許諾条件により本文は2020/11/01に公開
DOI: 10.14989/ActaUrolJap_65_10_429
URI: http://hdl.handle.net/2433/244698
PubMed ID: 31697890
Appears in Collections:Vol.65 No.10

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