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タイトル: | Dual color in situ hybridization(DISH)法により診断し得た後腹膜脱分化型脂肪肉腫の1例 |
その他のタイトル: | Retroperitoneal Dedifferentiated Liposarcoma which Could Be Diagnosed Using Dual Color in Situ Hybridization : A Case Report |
著者: | 飯沼, 光司 菱田, 勢始 伊藤, 裕基 谷口, 友規 髙井, 学 加藤, 大貴 村松(前川), 由佳 中根, 慶太 加藤, 卓 水谷, 晃輔 土屋, 朋大 東, 敏弥 村瀬, 勝俊 酒々井, 夏子 宮崎, 龍彦 古家, 琢也 |
著者名の別形: | Iinuma, Koji Hishida, Seiji Ito, Hiroki Taniguchi, Tomoki Takai, Manabu Kato, Daiki Muramatsu (Maekawa), Yuka Nakane, Keita Kato, Taku Mizutani, Kosuke Tsuchiya, Tomohiro Higashi, Toshiya Murase, Katsutoshi Suzui, Natsuko Miyazaki, Tatsuhiko Koie, Takuya |
キーワード: | Dedifferentiated liposarcoma Dual color in situ hybridization |
発行日: | 29-Feb-2020 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 66 |
号: | 2 |
開始ページ: | 45 |
終了ページ: | 48 |
抄録: | Ten years ago, a seventy-year-old female underwent extirpation of a left retroperitoneal tumor that was 58×36 mm in size. The pathological diagnosis was malignant peripheral nerve sheath tumor (MPNST) at that time. The patients visited our hospital with the chief complaint of back pain at ten years after surgery. Computer tomography (CT) showed recurrent tumors at the pancreas and the left kidney. Fine-needle aspiration biopsy was performed because of the possibility of pancreatic tumor. The pathological diagnosis was the recurrence of MPNST. The patient underwent extirpation of the recurrent tumors along with the pancreatic body and tail, transverse colon, spleen and left kidney. The definitive diagnosis was dedifferentiated liposarcoma with murine double minute 2 (MDM2) gene amplification and positive of p16Ink4 (p16). The previously resected tumor also revealed MDM2 gene amplification and positive of p16. Based on these results, our diagnosis in this case was recurrence of dedifferentiated liposarcoma. At 6 months after surgery, the patient had no local recurrence or distant metastases. |
著作権等: | 許諾条件により本文は2021/03/01に公開 |
DOI: | 10.14989/ActaUrolJap_66_2_45 |
URI: | http://hdl.handle.net/2433/246176 |
PubMed ID: | 32160732 |
出現コレクション: | Vol.66 No.2 |
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