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タイトル: | 去勢抵抗性前立腺癌治療中に発症した中枢神経原発悪性リンパ腫の1例 |
その他のタイトル: | A Case of Primary Central Nervous System Lymphoma that Developed during the Treatment of Castration-Resistant Prostate Cancer |
著者: | 弓場, 覚 中山, 雅志 栗林, 宗平 辻, 博隆 波多野, 浩士 中井, 康友 垣本, 健一 西村, 和郎 |
著者名の別形: | Yumiba, Satoru Nakayama, Masashi Kuribayashi, Sohei Tsuji, Hirotaka Hatano, Koji Nakai, Yasutomo Kakimoto, Ken-ichi Nishimura, Kazuo |
キーワード: | Brain metastasis of prostate cancer Primary central nervous system lymphoma |
発行日: | 29-Feb-2020 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 66 |
号: | 2 |
開始ページ: | 49 |
終了ページ: | 52 |
抄録: | A 64-year-old man was diagnosed with metastatic prostate cancer (cT3bN0M1b) and treated with combined androgen blockade. After two years and three months, he developed castration-resistant prostate cancer. Multiple lung metastases appeared after the administration of five courses of docetaxel and four courses of cabazitaxel therapy. Pulmonary metastases disappeared following rechallenge with docetaxel. Enzalutamide administration was initiated because docetaxel had to be discontinued due to adverse events. Although enzalutamide lowered the prostate specific antigen value, the patient staggered while walking and developed homonymous hemianopsia. Magnetic resonance imaging revealed a brain tumor. Although the brain tumor was considered to have metastasized from the prostate cancer, it was diagnosed as a primary central nervous system lymphoma using open-ended tumor biopsy. The brain tumor was eliminated with whole-brain irradiation. Thereafter, he has been treated with enzalutamide for 3 years without clinical progression of either disease. |
著作権等: | 許諾条件により本文は2021/03/01に公開 |
DOI: | 10.14989/ActaUrolJap_66_2_49 |
URI: | http://hdl.handle.net/2433/246177 |
PubMed ID: | 32160733 |
出現コレクション: | Vol.66 No.2 |
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