ダウンロード数: 109
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
j.ejro.2018.01.003.pdf | 694.82 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | Iima, Mami | en |
dc.contributor.author | Kataoka, Masako | en |
dc.contributor.author | Sakaguchi, Rena | en |
dc.contributor.author | Kanao, Shotaro | en |
dc.contributor.author | Onishi, Natsuko | en |
dc.contributor.author | Kawai, Makiko | en |
dc.contributor.author | Ohashi, Akane | en |
dc.contributor.author | Murata, Katsutoshi | en |
dc.contributor.author | Togashi, Kaori | en |
dc.contributor.alternative | 飯間, 麻美 | ja |
dc.contributor.alternative | 片岡, 正子 | ja |
dc.contributor.alternative | 金尾, 昌太郎 | ja |
dc.contributor.alternative | 大西, 奈都子 | ja |
dc.contributor.alternative | 河合, 真喜子 | ja |
dc.contributor.alternative | 大橋, 茜 | ja |
dc.contributor.alternative | 村田, 勝俊 | ja |
dc.contributor.alternative | 富樫, かおり | ja |
dc.date.accessioned | 2020-03-26T06:41:47Z | - |
dc.date.available | 2020-03-26T06:41:47Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2352-0477 | - |
dc.identifier.uri | http://hdl.handle.net/2433/246439 | - |
dc.description.abstract | Purpose: To investigate the effect of breastfeeding on IVIM and non-Gaussian diffusion MRI in the breast. Materials and methods: An IRB approved prospective study enrolled seventeen volunteers (12 in lactation and 5 with post-weaning, range 31–43 years; mean 35.4 years). IVIM (fIVIM and D*) and non-Gaussian diffusion (ADC₀ and K) parameters using 16 b values, plus synthetic apparent diffusion coefficients (sADCs) from 2 key b values (b = 200 and 1500 s/mm²) were calculated using regions of interest. ADC₀ maps of the whole breast were generated and their contrast patterns were evaluated by two independent readers using retroareolar and segmental semi-quantitative scores. To compare the diffusion and IVIM parameters, Wilcoxon signed rank tests were used between pre- and post-breastfeeding and Mann-Whitney tests were used between post-weaning and pre- or post-breastfeeding. Results: ADC₀ and sADC values significantly decreased post-breastfeeding (1.90 vs. 1.72 × 10⁻³mn²/s, P < 0.001) while K values significantly increased (0.33 vs. 0.44, P < 0.05). fIVIM values significantly increased after breastfeeding (1.97 vs. 2.97%, P < 0.01). No significant difference was found in D* values. There was significant heterogeneity in ADC₀ maps post-breastfeeding, both in retroareolar and segmental scores (P < 0.0001 and =0.0001). Conclusion: IVIM and non-Gaussian diffusion parameters significantly changed between pre- and post-breastfeeding status, and care needs to be taken in interpreting diffusion-weighted imaging (DWI) data in lactating breasts. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier BV | en |
dc.rights | © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). | en |
dc.subject | Diffusion-weighted imaging | en |
dc.subject | Intravoxel incoherent motion | en |
dc.subject | Kurtosis | en |
dc.subject | Lactation | en |
dc.subject | Breast | en |
dc.title | Intravoxel incoherent motion (IVIM) and non-Gaussian diffusion MRI of the lactating breast | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | European Journal of Radiology Open | en |
dc.identifier.volume | 5 | - |
dc.identifier.spage | 24 | - |
dc.identifier.epage | 30 | - |
dc.relation.doi | 10.1016/j.ejro.2018.01.003 | - |
dc.textversion | publisher | - |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine・The Hakubi Center for Advanced Research, Kyoto University | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.address | Siemens Japan K.K. | en |
dc.address | Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine | en |
dc.identifier.pmid | 29719854 | - |
dcterms.accessRights | open access | - |
datacite.awardNumber | 15K19786 | - |
jpcoar.funderName | 日本学術振興会 | ja |
jpcoar.funderName.alternative | Japan Society for the Promotion of Science (JSPS) | en |
出現コレクション: | 学術雑誌掲載論文等 |
![](/dspace/image/articlelinker.gif)
このリポジトリに保管されているアイテムはすべて著作権により保護されています。