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タイトル: Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
著者: Yamazaki, Shota
Harata, Masahiko
Ueno, Yuya
Tsubouchi, Masaaki
Konagaya, Keiji
Ogawa, Yuichi  KAKEN_id  orcid https://orcid.org/0000-0002-2238-2615 (unconfirmed)
Isoyama, Goro
Otani, Chiko
Hoshina, Hiromichi
著者名の別形: 山崎, 祥他
原田, 昌彦
上野, 祐也
坪内, 雅明
小長谷, 圭志
小川, 雄一
磯山, 悟朗
大谷, 知行
保科, 宏道
キーワード: Cell biology
Optics and photonics
発行日: 2-Jun-2020
出版者: Springer Nature
誌名: Scientific Reports
巻: 10
論文番号: 9008
抄録: The effect of terahertz (THz) radiation on deep tissues of human body has been considered negligible due to strong absorption by water molecules. However, we observed that the energy of THz pulses transmits a millimeter thick in the aqueous solution, possibly as a shockwave, and demolishes actin filaments. Collapse of actin filament induced by THz irradiation was also observed in the living cells under an aqueous medium. We also confirmed that the viability of the cell was not affected under the exposure of THz pulses. The potential of THz waves as an invasive method to alter protein structure in the living cells is demonstrated.
記述: テラヘルツ光照射による細胞内タンパク質重合体の断片化を解明 --THzパルス光が衝撃波として生体内部へ到達する可能性--. 京都大学プレスリリース. 2020-06-03.
著作権等: © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
URI: http://hdl.handle.net/2433/251075
DOI(出版社版): 10.1038/s41598-020-65955-5
PubMed ID: 32488073
関連リンク: https://www.kyoto-u.ac.jp/ja/research-news/2020-06-03-0
出現コレクション:学術雑誌掲載論文等

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