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タイトル: | 男性下部尿路症状の処方薬に影響を及ぼす患者背景因子 : 宮崎県泌尿器科医療連携施設による多施設共同研究 |
その他のタイトル: | Patient Background Factors Affecting Prescription Drugs for Male Lower Urinary Tract Symptoms: The Multicenter Study of Miyazaki Urological-Network Group |
著者: | 月野, 浩昌 賀本, 敏行 |
著者名の別形: | Tsukino, Hiromasa Kamoto, Toshiyuki |
キーワード: | Male lower urinary tract symptoms Patient background factors Prescription drugs |
発行日: | 31-Dec-2020 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 66 |
号: | 12 |
開始ページ: | 433 |
終了ページ: | 438 |
抄録: | The present multicenter study performed by the MIYAZAKI UROLOGICAL-NETWORK GROUP involving patients from 32 hospitals in Miyazaki Prefecture demonstrates that an association exists between the use of prescription drugs for male lower urinary tract symptoms (MLUTS) and patient characteristics. Men aged ≥40 years who were prescribed at least one drug for MLUTS between April 1, 2014 and March 31, 2015 were prospectively recruited. In total, 2, 295 patients with a median age of 72 years were enrolled. The median prostate volume was 33 ml, the median International Prostate Symptom Score (IPSS) was 15, and the median quality-of-life score was 5. Prescribed drugs were α1-blockers alone in 1, 661 patients, tamsulosin hydrochloride in 702, silodosin in 481, and naftopidil in 477. Multivariate analysis of the associations between use of α1-blockers and patient characteristics revealed use of tamsulosin hydrochloride to be more significantly associated with higher age (P=0.02), higher prostate volume (P=0.048), and higher IPSS score (P=0. 01) than silodosin. No significant associations between patient characteristics and naftopidil or tamsulosin hydrochloride ware revealed. We found that 369 patients received drug therapy for MLUTS plus overactive bladder (OAB). Multivariate analysis of the associations between patient characteristics and use of drugs for MLUTS or MLUTS plus OAB revealed higher age (P=0.001) and lower PSA value (P=0.04), lower prostate volume (P=0.01), and higher storage symptom score of IPSS (P< 0.001) to be more strongly associated with use of drugs for MLUTS plus OAB than drugs for MLUTS alone. |
著作権等: | 許諾条件により本文は2022/01/01に公開 |
DOI: | 10.14989/ActaUrolJap_66_12_433 |
URI: | http://hdl.handle.net/2433/260986 |
PubMed ID: | 33435653 |
出現コレクション: | Vol.66 No.12 |
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