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ejoc.202001592.pdf | 17.01 MB | Adobe PDF | 見る/開く |
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DCフィールド | 値 | 言語 |
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dc.contributor.author | Uchino, Ayumi | en |
dc.contributor.author | Tsukano, Chihiro | en |
dc.contributor.author | Imamoto, Tsuneo | en |
dc.contributor.author | Irie, Kazuhiro | en |
dc.contributor.alternative | 内野, 歩美 | ja |
dc.contributor.alternative | 塚野, 千尋 | ja |
dc.contributor.alternative | 入江, 一浩 | ja |
dc.date.accessioned | 2021-03-05T02:34:31Z | - |
dc.date.available | 2021-03-05T02:34:31Z | - |
dc.date.issued | 2021-03-05 | - |
dc.identifier.issn | 1434-193X | - |
dc.identifier.issn | 1099-0690 | - |
dc.identifier.uri | http://hdl.handle.net/2433/261874 | - |
dc.description.abstract | Although bis‐α‐amino acids have been used to synthesize dimer models of aggregative peptides involved in neurodegenerative diseases, tris‐α‐amino acids are employed to a lesser extent for trimer models. The reported tris‐α‐amino acids substituted on the 1, 3, 5‐positions of an aromatic ring are not suitable for mimicking trimers due to their low flexibility and high planarity. Here, we design and synthesize two new alkyl bridged‐tris‐α‐amino acids with Fmoc protecting groups as new flexible linkers for trimer models. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley | en |
dc.rights | This is the peer reviewed version of the following article: A. Uchino, C. Tsukano, T. Imamoto, K. Irie, Eur. J. Org. Chem. 2021, 2021, 1370, which has been published in final form at https://doi.org/10.1002/ejoc.202001592. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | en |
dc.rights | The full-text file will be made open to the public on 5 March 2022 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. | en |
dc.rights | This is not the published version. Please cite only the published version. | en |
dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
dc.subject | Amino acids | en |
dc.subject | Amyloid beta-peptides | en |
dc.subject | Trimers | en |
dc.title | Synthesis of Alkyl Bridged‐Tris‐α‐Amino Acids as C₃‐Symmetric and Linear Linkers | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | European Journal of Organic Chemistry | en |
dc.identifier.volume | 2021 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 1370 | - |
dc.identifier.epage | 1377 | - |
dc.relation.doi | 10.1002/ejoc.202001592 | - |
dc.textversion | author | - |
dc.address | Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University | en |
dc.address | Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University | en |
dc.address | Department of Chemistry, Graduate School of Science, Chiba University | en |
dc.address | Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University | en |
dcterms.accessRights | open access | - |
datacite.date.available | 2022-03-05 | - |
datacite.awardNumber | 19H00921 | - |
jpcoar.funderName | 日本学術振興会 | ja |
jpcoar.funderName.alternative | Japan Society for the Promotion of Science (JSPS) | en |
出現コレクション: | 学術雑誌掲載論文等 |
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