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dc.contributor.authorMatsuda, Michiyukien
dc.contributor.authorTerai, Kentaen
dc.contributor.alternative松田, 道行ja
dc.contributor.alternative寺井, 健太ja
dc.date.accessioned2021-06-16T07:27:44Z-
dc.date.available2021-06-16T07:27:44Z-
dc.date.issued2020-06-
dc.identifier.urihttp://hdl.handle.net/2433/263337-
dc.description.abstractThe invention of two-photon excitation microscopes widens the potential application of intravital microscopy (IVM) to the broad field of experimental pathology. Moreover, the recent development of fluorescent protein-based, genetically encoded biosensors provides an ideal tool to visualize the cell function in live animals. We start from a brief review of IVM with two-photon excitation microscopes and genetically encoded biosensors based on the principle of Förster resonance energy transfer (FRET). Then, we describe how IVM using biosensors has revealed the pathogenesis of several disease models.en
dc.language.isoeng-
dc.publisherwileyen
dc.rights© 2020 The Authors. Pathology International published by Japanese Society of Pathology and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.en
dc.subjectbiosensoren
dc.subjectexperimental pathologyen
dc.subjectFRETen
dc.subjectintravital microscopen
dc.titleExperimental pathology by intravital microscopy and genetically encoded fluorescent biosensorsen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.jtitlePathology Internationalen
dc.identifier.volume70-
dc.identifier.issue7-
dc.identifier.spage379-
dc.identifier.epage390-
dc.relation.doi10.1111/pin.12925-
dc.textversionpublisher-
dc.identifier.pmid32270554-
dcterms.accessRightsopen access-
datacite.awardNumber11242209-
datacite.awardNumber16390078-
datacite.awardNumber17012014-
datacite.awardNumber19209008-
datacite.awardNumber22113002-
datacite.awardNumber15H02397-
datacite.awardNumber15H05949-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-11242209/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-16390078/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17012014/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19209008/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PLANNED-22113002/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-15H02397/-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/ja/grant/KAKENHI-PLANNED-15H05949/-
dc.identifier.pissn1320-5463-
dc.identifier.eissn1440-1827-
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.funderName日本学術振興会ja
jpcoar.awardTitle低分子量G蛋白が細胞膜で情報を受け取るメカニズムの可視化ja
jpcoar.awardTitleRhoファミリーG蛋白群の時空間的制御機構の解析ja
jpcoar.awardTitle細胞がん化過程の時空間制御機構の解析ja
jpcoar.awardTitle細胞小胞輸送に関わる低分子量GTP結合蛋白の蛍光イメージングによる時空間的解析ja
jpcoar.awardTitle細胞内情報伝達系の多次元FRETイメージングja
jpcoar.awardTitleFRETマウスを用いた生体イメージングja
jpcoar.awardTitle細胞間コミュニケーションのライブイメージングja
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
jpcoar.funderName.alternativeJapan Society for the Promotion of Science (JSPS)en
出現コレクション:学術雑誌掲載論文等

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