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タイトル: | 転移性腎癌に伴うStauffer症候群様の所見が分子標的治療により改善した1例 |
その他のタイトル: | A Case of Stauffer Syndrome-Like Findings Associated with Metastatic Renal Cell Cancer Improved by Molecular Targeted Therapy |
著者: | 伊藤, 歌織 髙森, 大樹 秋岡, 貴弘 飛田, 卓哉 岡部, 洸 木田, 和貴 寺田, 直樹 上村, 敏雄 向井, 尚一郎 賀本, 敏行 |
著者名の別形: | ITO, Kaoru TAKAMORI, Hiroki AKIOKA, Takahiro HIDA, Takuya OKABE, Ko KIDA, Kazutaka TERADA, Naoki KAMIMURA, Toshio MUKAI, Shoichiro KAMOTO, Toshiyuki |
キーワード: | Metastatic renal cell carcinoma Stauffer syndrome Hepatic dysfunction Chemotherapy |
発行日: | 31-Jul-2021 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 67 |
号: | 7 |
開始ページ: | 309 |
終了ページ: | 312 |
抄録: | We report a case of Stauffer syndrome-like findings in a patient with metastatic renal carcinoma treated by surgery and molecular targeted therapy. The patient was a 58-year-old woman diagnosed with renal carcinoma with multiple metastases. She had hepatosplenomegaly and hepatic dysfunction with elevated serum liver enzyme and IL-6 levels. Treatment with temsirolimus and axitinib reduced the size of the local and metastatic tumors and simultaneously improved the hepatosplenomegaly. The local tumor was excised by laparoscopic nephrectomy, treated with axitinib and then with nivolumab. With the reduction in the metastatic tumor size, serum liver enzyme and IL-6 levels decreased. It was suggested that molecular targeted therapy is an effective treatment when the findings of metastatic renal cell carcinoma, are similar to those of Stauffer syndrome. |
著作権等: | 許諾条件により本文は2022-08-01に公開 |
DOI: | 10.14989/ActaUrolJap_67_7_309 |
URI: | http://hdl.handle.net/2433/264734 |
PubMed ID: | 34353011 |
出現コレクション: | Vol.67 No.7 |
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