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タイトル: | 術前アキシチニブ・ペムブロリズマブ併用療法が有効であった下大静脈腫瘍塞栓を伴う淡明細胞型腎癌の1例 |
その他のタイトル: | Presurgical Treatment with Axitinib and Pembrolizumab Reduced Operation Risk by Downsizing the Vena Cava Tumor Thrombus in Clear Cell Renal Cell Carcinoma : A Case Report |
著者: | 稲葉, 草太 ![]() 佐々木, 豪 ![]() 服部, 優奈 ![]() 寺邊, 隆史 ![]() 加藤, 桃子 ![]() 東, 真一郎 ![]() 加藤, 学 ![]() 舛井, 覚 ![]() 吉尾, 裕子 ![]() 西川, 晃平 ![]() 早崎, 碧泉 ![]() 山中, 隆嗣 ![]() 内田, 克典 ![]() 井上, 貴博 ![]() |
著者名の別形: | INABA, Sota SASAKI, Takeshi HATTORI, Yuna TERABE, Takashi KATO, Momoko HIGASHI, Shinichiro KATO, Manabu MASUI, Satoru YOSHIO, Yuko NISHIKAWA, Kouhei HAYASAKI, Aoi YAMANAKA, Takashi UCHIDA, Katsunori INOUE, Takahiro |
キーワード: | Renal cell carcinoma Inferior vena cava thrombus Axitinib Pembrolizumab |
発行日: | 31-Oct-2021 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 67 |
号: | 10 |
開始ページ: | 443 |
終了ページ: | 447 |
抄録: | A woman in her seventies complained of chest pain during exertion and visited a local hospital. Computed tomographic scan showed right renal cell carcinoma with inferior vena cava (IVC) tumor thrombus extending above the diaphragm, and the patient was referred to our hospital. She was diagnosed with right renal cell carcinoma cT3cN0M0, with level IV IVC thrombus by Mayo classification. Axitinib and pembrolizumab were administered against intractable advanced renal cell carcinoma. The dose of axitinib was reduced due to grade 3 liver dysfunction. Right nephrectomy together with IVC thrombectomy was performed because the primary lesion had shrunk, and the level of IVC thrombus had become level III. The pathological results were clear cell carcinoma, pT3c, G3, Fuhrman grade3, INFA, v1, and ly0. Axitinib and pembrolizumab might be a presurgical option against an intractable renal cell carcinoma with an IVC thrombus. |
著作権等: | 許諾条件により本文は2022-11-01に公開 |
DOI: | 10.14989/ActaUrolJap_67_10_443 |
URI: | http://hdl.handle.net/2433/265864 |
PubMed ID: | 34742168 |
出現コレクション: | Vol.67 No.10 |
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