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タイトル: | ニボルマブ再投与で治療効果を示した転移性腎細胞癌の1例 |
その他のタイトル: | Successful Re-Administration of Nivolumab in Patient with Metastatic Renal Cell Carcinoma : A Case Report |
著者: | 笹川, 甫 沼倉, 一幸 中村, 岳 久木元, 隆 菊池, 茜恵 提箸, 隆一郎 山本, 竜平 小泉, 淳 奈良, 健平 神田, 壮平 齋藤, 満 成田, 伸太郎 井上, 高光 佐藤, 滋 羽渕, 友則 |
著者名の別形: | SASAGAWA, Hajime NUMAKURA, Kazuyuki NAKAMURA, Gaku KUKIMOTO, Takashi KIKUCHI, Akane SAGEHASHI, Ryuichiro YAMAMOTO, Ryohei KOIZUMI, Atsushi NARA, Taketoshi KANDA, Sohei SAITO, Mitsuru NARITA, Shintaro INOUE, Takamitsu SATOH, Shigeru HABUCHI, Tomonori |
キーワード: | Renal cell carcinoma Nivolumab Re-administration Neutrophil-to-lymphocyte ratio |
発行日: | 31-Dec-2021 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 67 |
号: | 12 |
開始ページ: | 525 |
終了ページ: | 528 |
抄録: | A 46-year-old woman was referred to our hospital with a left-sided renal tumor pointed out by ultrasonography at the time of a medical checkup.Computed tomography revealed a mass measuring 88×77×68 mm on the upper pole of the left kidney. She was diagnosed with cT2aN0M0 clear cell renal cell carcinoma. Laparoscopic left nephrectomy was performed uneventfully. Histopathological diagnosis was clear cell renal cell carcinoma, G2, v1, pT2. Four months after surgery, lung metastases appeared, and systemic therapy was given sequentially as follows ; sunitinib for 2 months, nivolumab for 8 months, axitinib for 17 months, and pazopanib for 2 months.However, metastases progressed, and a re-administration of nivolumab was planned. The nivolumab re-treatment resulted in a marked reduction in multiple lung metastases despite the previous failure by nivolumab treatment. There are few reports on the therapeutic effect of re-administration of nivolumab. We report a case of successful treatment by re-administration of nivolumab. |
著作権等: | 許諾条件により本文は2023/01/01に公開 |
DOI: | 10.14989/ActaUrolJap_67_12_525 |
URI: | http://hdl.handle.net/2433/267415 |
PubMed ID: | 34991292 |
出現コレクション: | Vol.67 No.12 |
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