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Title: 経会陰前立腺MRI-TRUS融合画像ガイド下生検の導入期における診断精度の検討
Other Titles: Diagnostic Accuracy of Transperineal MRI-Ultrasound Fusion Biopsy at the Introduction Period
Authors: 服部, 悠斗  KAKEN_name
河野, 仁  KAKEN_name
吉野, 喬之  KAKEN_name
増井, 仁彦  KAKEN_name
佐藤, 琢磨  KAKEN_name
嘉島, 相輝  KAKEN_name
佐野, 剛視  KAKEN_name
後藤, 崇之  KAKEN_name
澤田, 篤郎  KAKEN_name
赤松, 秀輔  KAKEN_name
小林, 恭  KAKEN_name
井上, 貴博  KAKEN_name
小川, 修  KAKEN_name
Author's alias: HATTORI, Yuto
YOSHINO, Takayuki
MASUI, Kimihiko
SATO, Takuma
SANO, Takeshi
GOTO, Takayuki
SAWADA, Atsuro
INOUE, Takahiro
OGAWA, Osamu
Keywords: Prostate cancer
MRI fusion biopsy
Radical prostatectomy
Issue Date: 30-Apr-2022
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 68
Issue: 4
Start page: 99
End page: 105
Abstract: Magnetic resonance imaging (MRI) ultrasound fusion biopsy is becoming popular owing to the better detection rate of clinically significant prostate cancer (csPCa). We retrospectively evaluated the accuracy of MRI-targeted biopsy during the period of introduction at a single academic center by comparing findings of its specimen and whole-mount histopathology. Between June 2018 and January 2021, 106 transperineal MRI-ultrasound fusion biopsies using BioJet software were performed. Among the cases, 15 subsequently underwent robotic-assisted laparoscopic radical prostatectomy and were eligible for analysis. This study included all regions of interest (ROIs) with a Prostate Imaging Reporting and Data System v2 category of 3 or greater on pre-biopsy MRI.For each lesion, grade group of MRI-targeted biopsy specimens and prostatectomy specimens were compared. From a total of 25 ROIs identified among 15 males, csPCa was found in 21 (84%) of the concordant locations of prostatectomy specimens. However, MRI-targeted biopsy could diagnose csPCa in only 12 (48%) of them. In the csPCa undetected group, the ROI volume was significantly smaller (median volume 0.23 ml vs 0.40 ml, p=0.03). We also found that in cases where PCa was not detected through MRI-targeted biopsy, the biopsy sample length was significantly shorter (median length 9 mm vs 17 mm, p=0.01). Our data suggest that failure of detecting PCa in MRI-targeted biopsy could be due to technical errors at the introduction period of the technique. A sufficient sampling length of 10 mm or more is desirable, especially for small lesions.
Rights: 許諾条件により本文は2023/05/01に公開
DOI: 10.14989/ActaUrolJap_68_4_99
PubMed ID: 35613897
Appears in Collections:Vol.68 No.4

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