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Title: 傍精巣に生じた低悪性線維粘液性肉腫の1例
Other Titles: Paratesticular Low-Grade Fibromyxoid Sarcoma: A Case Report
Authors: 杉野, 文哉  KAKEN_name
石田, 貴史  KAKEN_name
玉木, 正義  KAKEN_name
米田, 尚生  KAKEN_name
渡部, 直樹  KAKEN_name
田中, 卓二  KAKEN_name
Author's alias: SUGINO, Fumiya
ISHIDA, Takashi
TAMAKI, Masayoshi
TANAKA, Takuji
Keywords: Low-grade fibromyxoid sarcoma
Paratesticular sarcoma
Issue Date: 31-Aug-2022
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 68
Issue: 8
Start page: 277
End page: 280
Abstract: A 36-year-old man presented with painless swelling in the right side scrotum. Ultrasonography showed a hypoechoic tumor with mosaic pattern. Plain computed tomograghy (CT) revealed a 67 mm scrotal cystic lesion with low density area. We suspected an intrascrotal tumor and performed right side radical orchiectomy. The removed sample was yellow clear and elastic hard. A 7 cm multilocular cystic tumor was present on the head side of the normal testis. The cut-surface and the contents of the mass revealed a jelly-like viscous liquid. On the microscopic examination, the tumor was composed of mucinous stroma and spindle-shaped atypical cells with hyperchromatic oval nuclei and eosinophilic cytoplasm. There was a characteristic network of blood vessesls with hyperhyalinization in the myxoid zones. Immunohistochemically, CDK4, MDM2, AE1/AE3, S-100, Alpha-SMA and desmin were negative, but MUC4 showed focal cytoplasmic positivity in the neoplastic cells. In the reverse transcription polymerase chain reaction assay, no FUS-CREB3L2/FUS-CREB3L1 fusion transcripts were identified although the detectable messages of the housekeeping genes were noted. The tumour was finally diagnosed as a paratesticular low-grade fibromyxoid sarcoma. Postoperative course was uneventful and no recurrence or metastasis was seen four months after the operation.
Rights: 許諾条件により本文は2023-09-01に公開
DOI: 10.14989/ActaUrolJap_68_8_277
PubMed ID: 36071020
Appears in Collections:Vol.68 No.8

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