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ファイル | 記述 | サイズ | フォーマット | |
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j.stemcr.2021.03.023.pdf | 1.19 MB | Adobe PDF | 見る/開く |
タイトル: | Biomedical and societal impacts of in vitro embryo models of mammalian development |
著者: | Moris, Naomi Alev, Cantas https://orcid.org/0000-0002-4879-8782 (unconfirmed) Pera, Martin Martinez Arias, Alfonso |
キーワード: | Pluripotent stem cells models of embryonic development ethics teratogens disease models |
発行日: | 11-May-2021 |
出版者: | Elsevier BV |
誌名: | Stem Cell Reports |
巻: | 16 |
号: | 5 |
開始ページ: | 1021 |
終了ページ: | 1030 |
抄録: | In recent years, a diverse array of in vitro cell-derived models of mammalian development have been described that hold immense potential for exploring fundamental questions in developmental biology, particularly in the case of the human embryo where ethical and technical limitations restrict research. These models open up new avenues toward biomedical advances in in vitro fertilization, clinical research, and drug screening with potential to impact wider society across many diverse fields. These technologies raise challenging questions with profound ethical, regulatory, and social implications that deserve due consideration. Here, we discuss the potential impacts of embryo-like models, and their biomedical potential and current limitations. |
著作権等: | © 2021 The Author(s). This is an open access article under the CC BY-NC-ND license. |
URI: | http://hdl.handle.net/2433/278210 |
DOI(出版社版): | 10.1016/j.stemcr.2021.03.023 |
PubMed ID: | 33979591 |
出現コレクション: | 学術雑誌掲載論文等 |
このアイテムは次のライセンスが設定されています: クリエイティブ・コモンズ・ライセンス