ダウンロード数: 119
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
19490976.2022.2161271.pdf | 4.36 MB | Adobe PDF | 見る/開く |
タイトル: | Host metabolic benefits of prebiotic exopolysaccharides produced by Leuconostoc mesenteroides |
著者: | Miyamoto, Junki Shimizu, Hidenori Hisa, Keiko Matsuzaki, Chiaki Inuki, Shinsuke https://orcid.org/0000-0002-7525-1280 (unconfirmed) Ando, Yuna Nishida, Akari Izumi, Ayano Yamano, Mayu Ushiroda, Chihiro Irie, Junichiro Katayama, Takane Ohno, Hiroaki https://orcid.org/0000-0002-3246-4809 (unconfirmed) Itoh, Hiroshi Yamamoto, Kenji Kimura, Ikuo |
著者名の別形: | 宮本, 潤基 清水, 秀憲 久, 景子 松崎, 千秋 井貫, 晋輔 安藤, 有菜 西田, 朱里 泉, 綾乃 山野, 真由 後田, ちひろ 入江, 潤一郎 片山, 高嶺 大野, 浩章 伊藤, 裕 山本, 憲二 木村, 郁夫 |
キーワード: | Exopolysaccharides short-chain fatty acids dietary fiber prebiotics obesity gut microbiota |
発行日: | 2023 |
出版者: | Taylor & Francis |
誌名: | Gut Microbes |
巻: | 15 |
号: | 1 |
論文番号: | 2161271 |
抄録: | Fermented foods demonstrate remarkable health benefits owing to probiotic bacteria or microproducts produced via bacterial fermentation. Fermented foods are produced by the fermentative action of several lactic acid bacteria, including Leuconostoc mesenteroides; however, the exact mechanism of action of these foods remains unclear. Here, we observed that prebiotics associated with L. mesenteroides-produced exopolysaccharides (EPS) demonstrate substantial host metabolic benefits. L. mesenteroides-produced EPS is an indigestible α-glucan, and intake of the purified form of EPS improved glucose metabolism and energy homeostasis through EPS-derived gut microbial short-chain fatty acids, and changed gut microbial composition. Our findings reveal an important mechanism that accounts for the effects of diet, prebiotics, and probiotics on energy homeostasis and suggests an approach for preventing lifestyle-related diseases by targeting bacterial EPS. |
記述: | 乳酸菌が作る菌体外多糖による腸内環境改善と肥満抑制 --新世代ポストバイオティクス成分EPSの機能性とシンバイオティクス乳酸菌--. 京都大学プレスリリース. 2023-01-18. |
著作権等: | © 2023 The Author(s). Published with license by Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
URI: | http://hdl.handle.net/2433/278700 |
DOI(出版社版): | 10.1080/19490976.2022.2161271 |
PubMed ID: | 36604628 |
関連リンク: | https://www.kyoto-u.ac.jp/ja/research-news/2023-01-18-3 |
出現コレクション: | 学術雑誌掲載論文等 |
このアイテムは次のライセンスが設定されています: クリエイティブ・コモンズ・ライセンス