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journal.pbio.3001945.pdf | 5.24 MB | Adobe PDF | 見る/開く |
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DCフィールド | 値 | 言語 |
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dc.contributor.author | Sugihara, Yu | en |
dc.contributor.author | Abe, Yoshiko | en |
dc.contributor.author | Takagi, Hiroki | en |
dc.contributor.author | Abe, Akira | en |
dc.contributor.author | Shimizu, Motoki | en |
dc.contributor.author | Ito, Kazue | en |
dc.contributor.author | Kanzaki, Eiko | en |
dc.contributor.author | Oikawa, Kaori | en |
dc.contributor.author | Kourelis, Jiorgos | en |
dc.contributor.author | Langner, Thorsten | en |
dc.contributor.author | Win, Joe | en |
dc.contributor.author | Białas, Aleksandra | en |
dc.contributor.author | Lüdke, Daniel | en |
dc.contributor.author | Contreras, Mauricio P. | en |
dc.contributor.author | Chuma, Izumi | en |
dc.contributor.author | Saitoh, Hiromasa | en |
dc.contributor.author | Kobayashi, Michie | en |
dc.contributor.author | Zheng, Shuan | en |
dc.contributor.author | Tosa, Yukio | en |
dc.contributor.author | Banfield, Mark J. | en |
dc.contributor.author | Kamoun, Sophien | en |
dc.contributor.author | Terauchi, Ryohei | en |
dc.contributor.author | Fujisaki, Koki | en |
dc.contributor.alternative | 杉原, 優 | ja |
dc.contributor.alternative | 阿部, 善子 | ja |
dc.contributor.alternative | 高木, 宏樹 | ja |
dc.contributor.alternative | 阿部, 陽 | ja |
dc.contributor.alternative | 清水, 元樹 | ja |
dc.contributor.alternative | 伊藤, 和江 | ja |
dc.contributor.alternative | 神崎, 英子 | ja |
dc.contributor.alternative | 及川, 香梨 | ja |
dc.contributor.alternative | 中馬, いづみ | ja |
dc.contributor.alternative | 齋藤, 宏昌 | ja |
dc.contributor.alternative | 小林, 光智衣 | ja |
dc.contributor.alternative | 土佐, 幸雄 | ja |
dc.contributor.alternative | 寺内, 良平 | ja |
dc.contributor.alternative | 藤﨑, 恒喜 | ja |
dc.date.accessioned | 2023-02-02T07:17:42Z | - |
dc.date.available | 2023-02-02T07:17:42Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.uri | http://hdl.handle.net/2433/279038 | - |
dc.description | ゲノム解読による植物病害抵抗性の解明 --イネ-いもち病菌「遺伝子対遺伝子」の戦い. 京都大学プレスリリース. 2023-02-01. | ja |
dc.description.abstract | Studies focused solely on single organisms can fail to identify the networks underlying host–pathogen gene-for-gene interactions. Here, we integrate genetic analyses of rice (Oryza sativa, host) and rice blast fungus (Magnaporthe oryzae, pathogen) and uncover a new pathogen recognition specificity of the rice nucleotide-binding domain and leucine-rich repeat protein (NLR) immune receptor Pik, which mediates resistance to M. oryzae expressing the avirulence effector gene AVR-Pik. Rice Piks-1, encoded by an allele of Pik-1, recognizes a previously unidentified effector encoded by the M. oryzae avirulence gene AVR-Mgk1, which is found on a mini-chromosome. AVR-Mgk1 has no sequence similarity to known AVR-Pik effectors and is prone to deletion from the mini-chromosome mediated by repeated Inago2 retrotransposon sequences. AVR-Mgk1 is detected by Piks-1 and by other Pik-1 alleles known to recognize AVR-Pik effectors; recognition is mediated by AVR-Mgk1 binding to the integrated heavy metal-associated (HMA) domain of Piks-1 and other Pik-1 alleles. Our findings highlight how complex gene-for-gene interaction networks can be disentangled by applying forward genetics approaches simultaneously to the host and pathogen. We demonstrate dynamic coevolution between an NLR integrated domain and multiple families of effector proteins. | en |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | en |
dc.rights | © 2023 Sugihara et al. | en |
dc.rights | This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | Rice | en |
dc.subject | Genomics | en |
dc.subject | Rice blast fungus | en |
dc.subject | Sequence alignment | en |
dc.subject | Host-pathogen interactions | en |
dc.subject | Genetic loci | en |
dc.subject | Single nucleotide polymorphisms | en |
dc.subject | Yeast two-hybrid assays | en |
dc.title | Disentangling the complex gene interaction networks between rice and the blast fungus identifies a new pathogen effector | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | PLOS Biology | en |
dc.identifier.volume | 21 | - |
dc.identifier.issue | 1 | - |
dc.relation.doi | 10.1371/journal.pbio.3001945 | - |
dc.textversion | publisher | - |
dc.identifier.artnum | e3001945 | - |
dc.address | Iwate Biotechnology Research Center; Crop Evolution Laboratory, Kyoto University; The Sainsbury Laboratory, University of East Anglia | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | Iwate Biotechnology Research Center; Current address: Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | Obihiro University of Agriculture and Veterinary Medicine | en |
dc.address | Iwate Biotechnology Research Center; Current address: Department of Molecular Microbiology, Tokyo University of Agriculture | en |
dc.address | Iwate Biotechnology Research Center; Current address: Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO) | en |
dc.address | Iwate Biotechnology Research Center; Crop Evolution Laboratory, Kyoto University | en |
dc.address | Graduate School of Agricultural Science, Kobe University | en |
dc.address | Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park | en |
dc.address | The Sainsbury Laboratory, University of East Anglia | en |
dc.address | Iwate Biotechnology Research Center; Crop Evolution Laboratory, Kyoto University | en |
dc.address | Iwate Biotechnology Research Center | en |
dc.identifier.pmid | 36656825 | - |
dc.relation.url | https://www.kyoto-u.ac.jp/ja/research-news/2023-02-01 | - |
dcterms.accessRights | open access | - |
datacite.awardNumber | 15H05779 | - |
datacite.awardNumber | 20H05681 | - |
datacite.awardNumber.uri | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H05779/ | - |
datacite.awardNumber.uri | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H05681/ | - |
dc.identifier.eissn | 1545-7885 | - |
jpcoar.funderName | 日本学術振興会 | ja |
jpcoar.funderName | 日本学術振興会 | ja |
jpcoar.awardTitle | イネ-いもち病相互作用の分子機構の解明 | ja |
jpcoar.awardTitle | イネNLR抵抗性遺伝子の機能と進化の解明 | ja |
出現コレクション: | 学術雑誌掲載論文等 |
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