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Title: Unsteady State Effectiveness Factor for Immobilized-Enzyme Reaction
Authors: HASHIMOTO, Kenji
ADACHI, Shuji
YOKOYAMA, Masaru
Issue Date: 31-Oct-1985
Publisher: Faculty of Engineering, Kyoto University
Journal title: Memoirs of the Faculty of Engineering, Kyoto University
Volume: 47
Issue: 4
Start page: 269
End page: 275
Abstract: The unsteady state concentration profiles of substrate in immobilized-enzyme particles were calculated numerically for the Michaelis-Menten kinetics. The analytical solution of the profile was also derived when the reaction was approximated to be of the first-order. The integration of the profile gives an unsteady state effectiveness factor. The unsteady state effectiveness factor was obtained under various conditions. The critical time at which a pseudo-steady state approximately holds, was presented graphically as a function of the steady state effectiveness factor for various V₀( =Kₘ/Cᴀ₀) values. The charts indicate that the pseudo-steady state is achived within 10-20s under usual operating conditions.
URI: http://hdl.handle.net/2433/281306
Appears in Collections:Vol.47 Part 4

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