このアイテムのアクセス数: 134
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.scr.2022.102696.pdf | 4.11 MB | Adobe PDF | 見る/開く |
| タイトル: | Generation of a human SOX10 knock-in reporter iPSC line for visualization of neural crest cell differentiation |
| 著者: | Yamashita, Teruyoshi Kamiya, Daisuke Kawaraichi, Nami Toyokawa, Harufu Akaboshi, Teppei Ikeya, Makoto    https://orcid.org/0000-0002-3930-8032 (unconfirmed)Toyooka, Yayoi |
| 著者名の別形: | 上谷, 大介 赤星, 哲平 池谷, 真 豊岡, やよい |
| 発行日: | Apr-2022 |
| 出版者: | Elsevier BV |
| 誌名: | Stem Cell Research |
| 巻: | 60 |
| 論文番号: | 102696 |
| 抄録: | SOX10 (SRY-box transcription factor 10) is not only a definitive molecular marker of neural crest cells (NCCs) but also an essential transcription factor for the differentiation of NCCs in vertebrate embryogenesis. Here, we report the establishment of a human SOX10 knock-in reporter iPSC line (SOX10-tdT) by CRISPR/Cas9-mediated homologous recombination, in which the expression of SOX10 can be monitored as tdTomato fluorescence. This iPSC line can provide a useful tool to model the differentiation process of human NCCs in vitro. |
| 著作権等: | © 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. |
| URI: | http://hdl.handle.net/2433/283264 |
| DOI(出版社版): | 10.1016/j.scr.2022.102696 |
| PubMed ID: | 35144211 |
| 出現コレクション: | 学術雑誌掲載論文等 |
このアイテムは次のライセンスが設定されています: クリエイティブ・コモンズ・ライセンス
